diff --git a/eng/Versions.props b/eng/Versions.props
index c4e792f83d7b32..3fcd1b86e3ef20 100644
--- a/eng/Versions.props
+++ b/eng/Versions.props
@@ -1,16 +1,18 @@
 <Project>
   <PropertyGroup>
     <!-- The .NET product branding version -->
-    <ProductVersion>5.0.0</ProductVersion>
+    <ProductVersion>6.0.0</ProductVersion>
     <!-- File version numbers -->
-    <MajorVersion>5</MajorVersion>
+    <MajorVersion>6</MajorVersion>
     <MinorVersion>0</MinorVersion>
     <PatchVersion>0</PatchVersion>
-    <PreReleaseVersionLabel>rc</PreReleaseVersionLabel>
+    <PreReleaseVersionLabel>alpha</PreReleaseVersionLabel>
     <PreReleaseVersionIteration>1</PreReleaseVersionIteration>
     <!-- Set assembly version to align with major and minor version,
          as for the patches and revisions should be manually updated per assembly if it is serviced. -->
-    <AssemblyVersion>$(MajorVersion).$(MinorVersion).0.0</AssemblyVersion>
+    <!-- Changing assembly versions without changing TFM lead to broken packages.
+         This shoud be incremented after introducing the 6.0 TFM. -->
+    <AssemblyVersion>5.0.0.0</AssemblyVersion>
     <!-- Enable to remove prerelease label. -->
     <StabilizePackageVersion Condition="'$(StabilizePackageVersion)' == ''">false</StabilizePackageVersion>
     <DotNetFinalVersionKind Condition="'$(StabilizePackageVersion)' == 'true'">release</DotNetFinalVersionKind>
diff --git a/eng/packaging.props b/eng/packaging.props
index d723eddfea5a1e..06c250ee1b99d5 100644
--- a/eng/packaging.props
+++ b/eng/packaging.props
@@ -20,7 +20,7 @@
     <SkipBaseLineCheck>true</SkipBaseLineCheck>
 
     <!-- by default all packages will use the same version which revs with respect to product version -->
-    <PackageVersion Condition="'$(PackageVersion)' == ''">5.0.0</PackageVersion>
+    <PackageVersion Condition="'$(PackageVersion)' == ''">6.0.0</PackageVersion>
     <!-- major.minor.release version of the platforms package we're currently building
          Pre-release will be appended during build -->
     <PlatformPackageVersion>$(ProductVersion)</PlatformPackageVersion>
diff --git a/eng/pipelines/coreclr/templates/perf-job.yml b/eng/pipelines/coreclr/templates/perf-job.yml
index ab098c58a567ba..dd08600f38b122 100644
--- a/eng/pipelines/coreclr/templates/perf-job.yml
+++ b/eng/pipelines/coreclr/templates/perf-job.yml
@@ -104,7 +104,7 @@ jobs:
           downloadPath: '$(Build.SourcesDirectory)/__download__'
           artifactName: 'IntermediateUnsignedArtifacts'
 
-      - script: "mkdir $(librariesDownloadDir)/bin/wasm;unzip -o $(Build.SourcesDirectory)/__download__/IntermediateUnsignedArtifacts/MonoRuntimePacks/Shipping/Microsoft.NETCore.App.Runtime.browser-wasm.5.0.0-ci.nupkg data/* runtimes/* -d $(librariesDownloadDir)/bin/wasm;cp src/mono/wasm/runtime-test.js $(librariesDownloadDir)/bin/wasm/runtime-test.js;find $(librariesDownloadDir)/bin/wasm -type f -exec chmod 664 {} \\;"
+      - script: "mkdir $(librariesDownloadDir)/bin/wasm;unzip -o $(Build.SourcesDirectory)/__download__/IntermediateUnsignedArtifacts/MonoRuntimePacks/Shipping/Microsoft.NETCore.App.Runtime.browser-wasm.6.0.0-ci.nupkg data/* runtimes/* -d $(librariesDownloadDir)/bin/wasm;cp src/mono/wasm/runtime-test.js $(librariesDownloadDir)/bin/wasm/runtime-test.js;find $(librariesDownloadDir)/bin/wasm -type f -exec chmod 664 {} \\;"
         displayName: "Create wasm directory (Linux)"
 
     # Create Core_Root
@@ -114,10 +114,10 @@ jobs:
 
       # Copy the runtime directory into the testhost folder to include OOBs.
 
-    - script: "build.cmd -subset libs.pretest -configuration release -ci -arch $(archType) -testscope innerloop /p:RuntimeArtifactsPath=$(librariesDownloadDir)\\bin\\mono\\$(osGroup).$(archType).$(buildConfigUpper) /p:RuntimeFlavor=mono;xcopy $(Build.SourcesDirectory)\\artifacts\\bin\\runtime\\$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)\\* $(Build.SourcesDirectory)\\artifacts\\bin\\testhost\\$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)\\shared\\Microsoft.NETCore.App\\5.0.0 /E /I /Y;xcopy $(Build.SourcesDirectory)\\artifacts\\bin\\testhost\\$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)\\* $(Build.SourcesDirectory)\\.dotnet-mono /E /I /Y;copy $(Build.SourcesDirectory)\\artifacts\\bin\\coreclr\\$(osGroup).$(archType).$(buildConfigUpper)\\corerun.exe $(Build.SourcesDirectory)\\.dotnet-mono\\shared\\Microsoft.NETCore.App\\5.0.0\\corerun.exe"
+    - script: "build.cmd -subset libs.pretest -configuration release -ci -arch $(archType) -testscope innerloop /p:RuntimeArtifactsPath=$(librariesDownloadDir)\\bin\\mono\\$(osGroup).$(archType).$(buildConfigUpper) /p:RuntimeFlavor=mono;xcopy $(Build.SourcesDirectory)\\artifacts\\bin\\runtime\\$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)\\* $(Build.SourcesDirectory)\\artifacts\\bin\\testhost\\$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)\\shared\\Microsoft.NETCore.App\\6.0.0 /E /I /Y;xcopy $(Build.SourcesDirectory)\\artifacts\\bin\\testhost\\$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)\\* $(Build.SourcesDirectory)\\.dotnet-mono /E /I /Y;copy $(Build.SourcesDirectory)\\artifacts\\bin\\coreclr\\$(osGroup).$(archType).$(buildConfigUpper)\\corerun.exe $(Build.SourcesDirectory)\\.dotnet-mono\\shared\\Microsoft.NETCore.App\\6.0.0\\corerun.exe"
       displayName: "Create mono dotnet (Windows)"
       condition: and(and(succeeded(), eq(variables.runtimeFlavorName, 'Mono')), eq(variables.osGroup, 'Windows_NT'))
 
-    - script: "mkdir $(Build.SourcesDirectory)/.dotnet-mono;./build.sh -subset libs.pretest -configuration release -ci -arch $(archType) -testscope innerloop /p:RuntimeArtifactsPath=$(librariesDownloadDir)/bin/mono/$(osGroup).$(archType).$(buildConfigUpper) /p:RuntimeFlavor=mono;cp $(Build.SourcesDirectory)/artifacts/bin/runtime/$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)/* $(Build.SourcesDirectory)/artifacts/bin/testhost/$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)/shared/Microsoft.NETCore.App/5.0.0 -rf;cp $(Build.SourcesDirectory)/artifacts/bin/testhost/$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)/* $(Build.SourcesDirectory)/.dotnet-mono -r;cp $(Build.SourcesDirectory)/artifacts/bin/coreclr/$(osGroup).$(archType).$(buildConfigUpper)/corerun $(Build.SourcesDirectory)/.dotnet-mono/shared/Microsoft.NETCore.App/5.0.0/corerun"
+    - script: "mkdir $(Build.SourcesDirectory)/.dotnet-mono;./build.sh -subset libs.pretest -configuration release -ci -arch $(archType) -testscope innerloop /p:RuntimeArtifactsPath=$(librariesDownloadDir)/bin/mono/$(osGroup).$(archType).$(buildConfigUpper) /p:RuntimeFlavor=mono;cp $(Build.SourcesDirectory)/artifacts/bin/runtime/$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)/* $(Build.SourcesDirectory)/artifacts/bin/testhost/$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)/shared/Microsoft.NETCore.App/6.0.0 -rf;cp $(Build.SourcesDirectory)/artifacts/bin/testhost/$(_Framework)-$(osGroup)-$(buildConfigUpper)-$(archType)/* $(Build.SourcesDirectory)/.dotnet-mono -r;cp $(Build.SourcesDirectory)/artifacts/bin/coreclr/$(osGroup).$(archType).$(buildConfigUpper)/corerun $(Build.SourcesDirectory)/.dotnet-mono/shared/Microsoft.NETCore.App/6.0.0/corerun"
       displayName: "Create mono dotnet (Linux)"
       condition: and(and(succeeded(), eq(variables.runtimeFlavorName, 'Mono')), ne(variables.osGroup, 'Windows_NT'))
diff --git a/src/coreclr/dir.common.props b/src/coreclr/dir.common.props
index f45eb84e8f277a..9dca67abfb99bc 100644
--- a/src/coreclr/dir.common.props
+++ b/src/coreclr/dir.common.props
@@ -43,7 +43,7 @@
 
   <PropertyGroup>
     <!-- Central place to set the versions of all nuget packages produced in the repo -->
-    <PackageVersion Condition="'$(PackageVersion)' == ''">5.0.0</PackageVersion>
+    <PackageVersion Condition="'$(PackageVersion)' == ''">6.0.0</PackageVersion>
 
     <!-- Set the boolean below to true to generate packages with stabilized versions -->
     <StabilizePackageVersion Condition="'$(StabilizePackageVersion)' == ''">false</StabilizePackageVersion>
diff --git a/src/coreclr/src/.nuget/Microsoft.NET.Sdk.IL/targets/Microsoft.NET.Sdk.IL.targets b/src/coreclr/src/.nuget/Microsoft.NET.Sdk.IL/targets/Microsoft.NET.Sdk.IL.targets
index 9a4272c394798c..3389fc5814984c 100644
--- a/src/coreclr/src/.nuget/Microsoft.NET.Sdk.IL/targets/Microsoft.NET.Sdk.IL.targets
+++ b/src/coreclr/src/.nuget/Microsoft.NET.Sdk.IL/targets/Microsoft.NET.Sdk.IL.targets
@@ -30,7 +30,7 @@ Copyright (c) .NET Foundation. All rights reserved.
     <_OSArchitecture>$([System.Runtime.InteropServices.RuntimeInformation]::OSArchitecture)</_OSArchitecture>
 
     <MicrosoftNetCoreIlasmPackageRuntimeId Condition="'$(MicrosoftNetCoreIlasmPackageRuntimeId)' == ''">$(_OSPlatform)-$(_OSArchitecture.ToLower())</MicrosoftNetCoreIlasmPackageRuntimeId>
-    <MicrosoftNETCoreILAsmVersion Condition="'$(MicrosoftNETCoreILAsmVersion)' == ''">5.0.0</MicrosoftNETCoreILAsmVersion>
+    <MicrosoftNETCoreILAsmVersion Condition="'$(MicrosoftNETCoreILAsmVersion)' == ''">6.0.0</MicrosoftNETCoreILAsmVersion>
     <MicrosoftNetCoreIlasmPackageName>runtime.$(MicrosoftNetCoreIlasmPackageRuntimeId).microsoft.netcore.ilasm</MicrosoftNetCoreIlasmPackageName>
     <MicrosoftNetCoreIldasmPackageName>runtime.$(MicrosoftNetCoreIlasmPackageRuntimeId).microsoft.netcore.ildasm</MicrosoftNetCoreIldasmPackageName>
 
diff --git a/src/libraries/pkg/baseline/packageIndex.json b/src/libraries/pkg/baseline/packageIndex.json
index 427eb60f15f7fc..6457475b075e0a 100644
--- a/src/libraries/pkg/baseline/packageIndex.json
+++ b/src/libraries/pkg/baseline/packageIndex.json
@@ -24,11 +24,11 @@
       "StableVersions": [
         "1.0.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "1.0.0.0": "1.0.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Bcl.HashCode": {
@@ -137,13 +137,13 @@
         "2.0.1",
         "2.1.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "2.0.0.0": "2.0.0",
         "2.0.1.0": "2.0.1",
         "2.0.2.0": "2.1.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Caching.Abstractions": {
@@ -171,7 +171,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Caching.Memory": {
@@ -199,7 +199,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration": {
@@ -226,7 +226,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.Abstractions": {
@@ -253,7 +253,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.Binder": {
@@ -282,7 +282,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.CommandLine": {
@@ -309,7 +309,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.EnvironmentVariables": {
@@ -337,7 +337,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.FileExtensions": {
@@ -364,7 +364,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.Ini": {
@@ -391,7 +391,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.Json": {
@@ -418,7 +418,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.UserSecrets": {
@@ -445,7 +445,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Configuration.Xml": {
@@ -472,7 +472,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.DependencyInjection": {
@@ -496,7 +496,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.DependencyInjection.Abstractions": {
@@ -520,7 +520,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.DependencyModel": {
@@ -549,14 +549,14 @@
         "3.1.5",
         "3.1.6"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "3.1.3.0": "3.1.3",
         "3.1.4.0": "3.1.4",
         "3.1.5.0": "3.1.5",
         "3.1.6.0": "3.1.6",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.FileProviders.Abstractions": {
@@ -580,7 +580,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.FileProviders.Composite": {
@@ -604,7 +604,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.FileProviders.Physical": {
@@ -628,7 +628,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.FileSystemGlobbing": {
@@ -650,7 +650,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.HostFactoryResolver.Sources": {
@@ -671,7 +671,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Hosting.Abstractions": {
@@ -693,7 +693,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Http": {
@@ -711,7 +711,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging": {
@@ -738,7 +738,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging.Abstractions": {
@@ -765,7 +765,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging.Configuration": {
@@ -786,7 +786,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging.Console": {
@@ -813,7 +813,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging.Debug": {
@@ -840,7 +840,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging.EventLog": {
@@ -867,7 +867,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging.EventSource": {
@@ -891,7 +891,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Logging.TraceSource": {
@@ -918,7 +918,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Options": {
@@ -945,7 +945,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Options.ConfigurationExtensions": {
@@ -972,7 +972,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Options.DataAnnotations": {
@@ -988,7 +988,7 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Extensions.Primitives": {
@@ -1012,18 +1012,18 @@
       ],
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.IO.Redist": {
       "StableVersions": [
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.JScript": {
@@ -1053,7 +1053,7 @@
         "2.2.2",
         "3.0.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {}
     },
     "Microsoft.NETCore.Targets": {
@@ -1075,7 +1075,7 @@
         "2.1.0",
         "3.0.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {}
     },
     "Microsoft.Phone": {
@@ -1210,7 +1210,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.0.0",
@@ -1218,7 +1218,7 @@
         "4.1.0.0": "4.4.0",
         "4.1.1.0": "4.5.0",
         "4.1.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Win32.Registry.AccessControl": {
@@ -1229,7 +1229,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.0.0",
@@ -1237,7 +1237,7 @@
         "4.0.2.0": "4.4.0",
         "4.0.3.0": "4.5.0",
         "4.0.4.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Win32.SystemEvents": {
@@ -1245,12 +1245,12 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.5.0",
         "4.0.1.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Windows.Compatibility": {
@@ -1277,13 +1277,13 @@
         "2.0.0",
         "2.1.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "1.0.0.0": "1.0.0",
         "1.0.1.0": "1.1.0",
         "2.0.0.0": "2.0.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "Microsoft.Xna.Framework": {
@@ -1453,14 +1453,14 @@
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@@ -2105,13 +2105,13 @@
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@@ -2250,23 +2250,23 @@
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@@ -2887,13 +2887,13 @@
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@@ -3334,7 +3334,7 @@
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@@ -3828,7 +3828,7 @@
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@@ -3839,7 +3839,7 @@
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@@ -4283,12 +4283,12 @@
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@@ -4331,7 +4331,7 @@
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@@ -4481,7 +4481,7 @@
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@@ -4677,7 +4677,7 @@
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@@ -4780,18 +4780,18 @@
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@@ -4940,7 +4940,7 @@
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@@ -4965,7 +4965,7 @@
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@@ -4975,7 +4975,7 @@
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@@ -5160,7 +5160,7 @@
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@@ -5459,7 +5459,7 @@
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@@ -5489,7 +5489,7 @@
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@@ -5521,7 +5521,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "uap10.0.16299": "4.1.1.0"
       },
@@ -5531,7 +5531,7 @@
         "4.1.0.0": "4.4.0",
         "4.1.1.0": "4.5.0",
         "4.1.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.Claims": {
@@ -5598,7 +5598,7 @@
         "4.6.0",
         "4.6.1"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "monoandroid10": "Any",
         "monotouch10": "Any",
@@ -5617,7 +5617,7 @@
         "4.3.1.0": "4.5.0",
         "4.3.2.0": "4.6.0",
         "4.3.2.1": "4.6.1",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.Cryptography.Csp": {
@@ -5681,7 +5681,7 @@
         "4.5.1",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.0.0",
@@ -5690,7 +5690,7 @@
         "4.1.1.0": "4.5.0",
         "4.1.1.1": "4.5.1",
         "4.1.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.Cryptography.Pkcs": {
@@ -5703,7 +5703,7 @@
         "4.5.2",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.0.0",
@@ -5714,7 +5714,7 @@
         "4.0.3.2": "4.5.2",
         "4.0.4.0": "4.6.0",
         "4.1.0.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.Cryptography.Primitives": {
@@ -5750,7 +5750,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "monoandroid10": "Any",
         "monotouch10": "Any",
@@ -5765,7 +5765,7 @@
         "4.0.2.0": "4.4.0",
         "4.0.3.0": "4.5.0",
         "4.0.4.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.Cryptography.X509Certificates": {
@@ -5806,13 +5806,13 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.4.0",
         "4.0.1.0": "4.5.0",
         "4.0.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.Permissions": {
@@ -5822,13 +5822,13 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.4.0",
         "4.0.1.0": "4.5.0",
         "4.0.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.Principal": {
@@ -5882,7 +5882,7 @@
         "4.5.1",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "uap10.0.16299": "4.1.1.0"
       },
@@ -5893,7 +5893,7 @@
         "4.1.1.0": "4.5.0",
         "4.1.1.1": "4.5.1",
         "4.1.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Security.SecureString": {
@@ -6062,12 +6062,12 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.5.0",
         "4.0.1.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.ServiceModel.Web": {
@@ -6112,7 +6112,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.1.0.0": "4.1.0",
@@ -6120,7 +6120,7 @@
         "4.2.0.0": "4.4.0",
         "4.2.1.0": "4.5.0",
         "4.2.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Speech": {
@@ -6182,7 +6182,7 @@
         "4.5.1",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "netcoreapp3.0": "4.1.2.0",
         "net5.0": "5.0.0.0",
@@ -6201,7 +6201,7 @@
         "4.1.0.0": "4.4.0",
         "4.1.1.0": "4.5.0",
         "4.1.2.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Text.Encoding.Extensions": {
@@ -6258,7 +6258,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "netcoreapp3.0": "4.0.4.0",
         "net5.0": "5.0.0.0"
@@ -6269,21 +6269,21 @@
         "4.0.2.0": "4.4.0",
         "4.0.3.0": "4.5.0",
         "4.0.4.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Text.Json": {
       "StableVersions": [
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "netcoreapp3.0": "4.0.0.0",
         "net5.0": "5.0.0.0"
       },
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Text.RegularExpressions": {
@@ -6385,7 +6385,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.0.0",
@@ -6393,7 +6393,7 @@
         "4.0.2.0": "4.4.0",
         "4.0.3.0": "4.5.0",
         "4.0.4.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Threading.Channels": {
@@ -6401,7 +6401,7 @@
         "4.5.0",
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "netcoreapp3.0": "4.0.1.0",
         "net5.0": "5.0.0.0"
@@ -6409,7 +6409,7 @@
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.5.0",
         "4.0.1.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Threading.Overlapped": {
@@ -6495,7 +6495,7 @@
         "4.9.0",
         "4.10.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {
         "netcoreapp2.0": "4.6.2.0",
         "netcoreapp2.1": "4.6.3.0",
@@ -6510,7 +6510,7 @@
         "4.6.2.0": "4.8.0",
         "4.6.3.0": "4.9.0",
         "4.6.4.0": "4.10.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Threading.Tasks.Extensions": {
@@ -6683,11 +6683,11 @@
       }
     },
     "System.Utf8String.Experimental": {
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.ValueTuple": {
@@ -6847,11 +6847,11 @@
       "StableVersions": [
         "4.6.0"
       ],
-      "BaselineVersion": "5.0.0",
+      "BaselineVersion": "6.0.0",
       "InboxOn": {},
       "AssemblyVersionInPackageVersion": {
         "4.0.0.0": "4.6.0",
-        "5.0.0.0": "5.0.0"
+        "5.0.0.0": "6.0.0"
       }
     },
     "System.Windows.Forms": {
diff --git a/src/mono/Directory.Build.props b/src/mono/Directory.Build.props
index 4d54c4ed616927..52df5527fc9339 100644
--- a/src/mono/Directory.Build.props
+++ b/src/mono/Directory.Build.props
@@ -24,7 +24,7 @@
 
   <PropertyGroup>
     <!-- Central place to set the versions of all nuget packages produced in the repo -->
-    <PackageVersion Condition="'$(PackageVersion)' == ''">5.0.0</PackageVersion>
+    <PackageVersion Condition="'$(PackageVersion)' == ''">6.0.0</PackageVersion>
 
     <!-- Set the boolean below to true to generate packages with stabilized versions -->
     <StabilizePackageVersion Condition="'$(StabilizePackageVersion)' == ''">false</StabilizePackageVersion>