diff --git a/easybuild/easyblocks/r/reticulate.py b/easybuild/easyblocks/r/reticulate.py
new file mode 100644
index 00000000000..2367b9cb60e
--- /dev/null
+++ b/easybuild/easyblocks/r/reticulate.py
@@ -0,0 +1,56 @@
+##
+# Copyright 2009-2021 Ghent University
+#
+# This file is part of EasyBuild,
+# originally created by the HPC team of Ghent University (http://ugent.be/hpc/en),
+# with support of Ghent University (http://ugent.be/hpc),
+# the Flemish Supercomputer Centre (VSC) (https://www.vscentrum.be),
+# Flemish Research Foundation (FWO) (http://www.fwo.be/en)
+# and the Department of Economy, Science and Innovation (EWI) (http://www.ewi-vlaanderen.be/en).
+#
+# https://github.com/easybuilders/easybuild
+#
+# EasyBuild is free software: you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation v2.
+#
+# EasyBuild is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with EasyBuild.  If not, see <http://www.gnu.org/licenses/>.
+##
+"""
+EasyBuild support for building and installing reticulate R package, implemented as an easyblock
+
+@author: Samuel Moors (Vrije Universiteit Brussel)
+"""
+import os
+
+from easybuild.easyblocks.generic.rpackage import RPackage
+from easybuild.tools.modules import get_software_root
+
+
+class EB_reticulate(RPackage):
+    """Support for installing the reticulate R package."""
+
+    def run(self):
+        """Add extra environment variables to modulefile"""
+
+        txt = super(EB_reticulate, self).run()
+        if not txt:
+            txt = ""
+
+        pythonroot = get_software_root('Python')
+        if pythonroot:
+            # make sure EB-provided Python is used, and that reticulate does not install it's own Python
+            # see: https://rstudio.github.io/reticulate/reference/use_python.html
+            # see: https://github.com/rstudio/reticulate/issues/894
+            txt += self.module_generator.set_environment('RETICULATE_PYTHON', os.path.join(pythonroot, 'bin', 'python'))
+        else:
+            self.log.info("Python not included as dependency, so RETICULATE_PYTHON not set")
+
+        self.log.info("adding to modulefile: %s" % txt)
+        return txt