diff --git a/src/transformers/integrations/flex_attention.py b/src/transformers/integrations/flex_attention.py
index 240c23125724..a2532c891f3a 100644
--- a/src/transformers/integrations/flex_attention.py
+++ b/src/transformers/integrations/flex_attention.py
@@ -305,6 +305,17 @@ def score_mod(score, batch_idx, head_idx, q_idx, kv_idx):
         enable_gqa = False
 
     kernel_options = kwargs.get("kernel_options")
+    # The default block sizes fault at head_dim 512 on B300 (pytorch/pytorch#200348) and are 1.7x slower than 32-row
+    # blocks on H100 (e.g. Gemma 4 global layers). In fp32, 32-row blocks need ~200 KB of shared memory, which only
+    # Hopper and datacenter Blackwell have, so other GPUs keep the default blocks
+    if (
+        kernel_options is None
+        and query.shape[-1] > 256
+        and query.device.type == "cuda"
+        and torch.version.hip is None
+        and torch.cuda.get_device_capability(query.device)[0] in (9, 10)
+    ):
+        kernel_options = {"BLOCK_M": 32, "BLOCK_N": 32, "num_stages": 2, "num_warps": 4}
     # On CPU we must skip returning LSE due to a runtime issue; elsewhere, follow PyTorch API and return it
     return_lse = query.device.type != "cpu"
 
diff --git a/tests/integrations/test_flex_attention.py b/tests/integrations/test_flex_attention.py
new file mode 100644
index 000000000000..f1abd3271de5
--- /dev/null
+++ b/tests/integrations/test_flex_attention.py
@@ -0,0 +1,55 @@
+# Copyright 2026 The HuggingFace Team. All rights reserved.
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+import unittest
+
+from transformers.testing_utils import (
+    is_torch_available,
+    require_flex_attention,
+    require_torch_accelerator,
+    torch_device,
+)
+
+
+if is_torch_available():
+    import torch
+    from torch.nn.attention.flex_attention import create_block_mask
+
+    from transformers.integrations.flex_attention import flex_attention_forward
+
+
+@require_flex_attention
+@require_torch_accelerator
+class FlexAttentionForwardTest(unittest.TestCase):
+    def test_head_dim_512_forward_and_backward(self):
+        # Gemma 4 global layers use head_dim 512, where the default flex block sizes fault on Blackwell
+        torch.manual_seed(0)
+        batch_size, num_heads, num_kv_heads, seq_len, head_dim = 1, 8, 2, 1024, 512
+        query = torch.randn(batch_size, num_heads, seq_len, head_dim, device=torch_device, dtype=torch.bfloat16)
+        key = torch.randn(batch_size, num_kv_heads, seq_len, head_dim, device=torch_device, dtype=torch.bfloat16)
+        value = torch.randn(batch_size, num_kv_heads, seq_len, head_dim, device=torch_device, dtype=torch.bfloat16)
+        query.requires_grad_()
+        block_mask = create_block_mask(lambda b, h, q, kv: q >= kv, None, None, seq_len, seq_len, device=torch_device)
+
+        output, _ = flex_attention_forward(torch.nn.Module(), query, key, value, block_mask)
+        output.float().sum().backward()
+
+        reference_query = query.detach().float().requires_grad_()
+        reference = torch.nn.functional.scaled_dot_product_attention(
+            reference_query, key.float(), value.float(), is_causal=True, enable_gqa=True
+        )
+        reference.sum().backward()
+
+        torch.testing.assert_close(output.float(), reference.transpose(1, 2), rtol=2e-2, atol=2e-2)
+        torch.testing.assert_close(query.grad.float(), reference_query.grad, rtol=2e-2, atol=2e-2)