diff --git a/AutoDuck/makedfromi.py b/AutoDuck/makedfromi.py
index 53edf0111a..4db2a09f9b 100644
--- a/AutoDuck/makedfromi.py
+++ b/AutoDuck/makedfromi.py
@@ -32,7 +32,7 @@ def GetComments(line, lineNo, lines):
 
 
 def make_doc_summary(inFile, outFile):
-    methods = []
+    methods: list[tuple[str, list[str]]] = []
     modDoc = ""
     modName = ""
     lines = inFile.readlines()
diff --git a/AutoDuck/py2d.py b/AutoDuck/py2d.py
index 5550fb6b7d..c350a4864d 100644
--- a/AutoDuck/py2d.py
+++ b/AutoDuck/py2d.py
@@ -49,8 +49,8 @@ def should_build_function(build_info):
 
 # docstring aware paragraph generator.  Isn't there something in docutils
 # we can use?
-def gen_paras(val):
-    chunks = []
+def gen_paras(val: str):
+    chunks: list[str] = []
     in_docstring = False
     for line in val.splitlines():
         line = ad_escape(line.strip())
diff --git a/com/win32com/client/dynamic.py b/com/win32com/client/dynamic.py
index 3738da9031..c65d7e6aea 100644
--- a/com/win32com/client/dynamic.py
+++ b/com/win32com/client/dynamic.py
@@ -411,7 +411,7 @@ def _make_method_(self, name):
             # self._print_details_()
             codeObject = compile(methodCode, "<COMObject %s>" % self._username_, "exec")
             # Exec the code object
-            tempNameSpace = {}
+            tempNameSpace: dict[str, object] = {}
             # "Dispatch" in the exec'd code is win32com.client.Dispatch, not ours.
             globNameSpace = globals().copy()
             globNameSpace["Dispatch"] = win32com.client.Dispatch
diff --git a/com/win32comext/axdebug/codecontainer.py b/com/win32comext/axdebug/codecontainer.py
index bc4ec4af71..26aaf2a09a 100644
--- a/com/win32comext/axdebug/codecontainer.py
+++ b/com/win32comext/axdebug/codecontainer.py
@@ -129,7 +129,7 @@ def _ProcessToken(self, type, token, spos, epos, line):
         erow, ecol = epos
         self.GetText()  # Prime us.
         linenum = srow - 1  # Lines zero based for us too.
-        realCharPos = self.lineOffsets[linenum] + scol
+        realCharPos: int = self.lineOffsets[linenum] + scol
         numskipped = realCharPos - self.lastPos
         if numskipped == 0:
             pass
@@ -162,7 +162,7 @@ def _ProcessToken(self, type, token, spos, epos, line):
 
     def GetSyntaxColorAttributes(self):
         self.lastPos = 0
-        self.attrs = []
+        self.attrs: list[tuple[int] | tuple[int, int]] = []
         try:
             for tokens in tokenize.tokenize(self.GetNextLine):
                 self._ProcessToken(*tokens)
diff --git a/com/win32comext/axscript/client/pyscript.py b/com/win32comext/axscript/client/pyscript.py
index 0e36029436..28b7b59686 100644
--- a/com/win32comext/axscript/client/pyscript.py
+++ b/com/win32comext/axscript/client/pyscript.py
@@ -7,6 +7,8 @@
 command line.
 """
 
+from __future__ import annotations
+
 import re
 import types
 
@@ -286,7 +288,7 @@ def GetScriptDispatch(self, name):
             )
         return self.scriptDispatch
 
-    def MakeEventMethodName(self, subItemName, eventName):
+    def MakeEventMethodName(self, subItemName: str, eventName: str):
         return (
             subItemName[0].upper()
             + subItemName[1:]
diff --git a/mypy.ini b/mypy.ini
index 69dca8f198..32f4c92b70 100644
--- a/mypy.ini
+++ b/mypy.ini
@@ -42,10 +42,8 @@ disable_error_code =
     ; list-item,
     ; operator,
     ; override,
-    ; str-format,
     ; type-var,
     ; union-attr,
-    ; valid-type,
     ; var-annotated,
     ; ; And these only happen when checking against types-pywin32
     ; func-returns-value,
diff --git a/pythonwin/pywin/debugger/dbgcon.py b/pythonwin/pywin/debugger/dbgcon.py
index c3a33c417d..8a1101a2e7 100644
--- a/pythonwin/pywin/debugger/dbgcon.py
+++ b/pythonwin/pywin/debugger/dbgcon.py
@@ -20,7 +20,7 @@ def DoGetOption(optsDict, optName, default):
 
 
 def LoadDebuggerOptions():
-    opts = {}
+    opts: dict[str, str] = {}
     DoGetOption(opts, OPT_HIDE, 0)
     DoGetOption(opts, OPT_STOP_EXCEPTIONS, 1)
     return opts
diff --git a/pythonwin/pywin/framework/help.py b/pythonwin/pywin/framework/help.py
index 7467d2f8fb..a91f2e1a22 100644
--- a/pythonwin/pywin/framework/help.py
+++ b/pythonwin/pywin/framework/help.py
@@ -80,7 +80,7 @@ def ListAllHelpFiles():
 def _ListAllHelpFilesInRoot(root):
     """Returns a list of (helpDesc, helpFname) for all registered help files"""
 
-    retList = []
+    retList: list[tuple[str, str]] = []
     try:
         key = win32api.RegOpenKey(
             root, regutil.BuildDefaultPythonKey() + "\\Help", 0, win32con.KEY_READ
diff --git a/pythonwin/pywin/framework/interact.py b/pythonwin/pywin/framework/interact.py
index 9541f9c5d9..8bcd1dd5c6 100644
--- a/pythonwin/pywin/framework/interact.py
+++ b/pythonwin/pywin/framework/interact.py
@@ -482,7 +482,7 @@ def GetBlockBoundary(self, lineNo):
 
     def ExtractCommand(self, lines):
         start, end = lines
-        retList = []
+        retList: list[str] = []
         while end >= start:
             thisLine = self.DoGetLine(end)
             promptLen = len(GetPromptPrefix(thisLine))
diff --git a/pythonwin/pywin/framework/scriptutils.py b/pythonwin/pywin/framework/scriptutils.py
index abf5a40c13..676e9742ac 100644
--- a/pythonwin/pywin/framework/scriptutils.py
+++ b/pythonwin/pywin/framework/scriptutils.py
@@ -439,7 +439,7 @@ def ImportFile():
     # meaning sys.modules can change as a side-effect of looking at
     # module.__file__ - so we must take a copy (ie, list(items()))
     for key, mod in sys.modules.items():
-        if getattr(mod, "__file__", None):
+        if hasattr(mod, "__file__") and mod.__file__:
             fname = mod.__file__
             base, ext = os.path.splitext(fname)
             if ext.lower() in (".pyo", ".pyc"):
@@ -547,14 +547,13 @@ def RunTabNanny(filename):
     data = newout.getvalue()
     if data:
         try:
-            lineno = data.split()[1]
-            lineno = int(lineno)
+            lineno = int(data.split()[1])
             _JumpToPosition(filename, lineno)
             try:  # Try and display whitespace
                 GetActiveEditControl().SCISetViewWS(1)
             except:
                 pass
-            win32ui.SetStatusText("The TabNanny found trouble at line %d" % lineno)
+            win32ui.SetStatusText(f"The TabNanny found trouble at line {lineno}")
         except (IndexError, TypeError, ValueError):
             print("The tab nanny complained, but I can't see where!")
             print(data)
diff --git a/pythonwin/pywin/framework/winout.py b/pythonwin/pywin/framework/winout.py
index c98c98ff85..6be5a60014 100644
--- a/pythonwin/pywin/framework/winout.py
+++ b/pythonwin/pywin/framework/winout.py
@@ -380,7 +380,7 @@ def __init__(
             self.iniSizeSection = None
             self.defSize = defSize
         self.currentView = None
-        self.outputQueue = queue.Queue(-1)
+        self.outputQueue: queue.Queue[str] = queue.Queue(-1)
         self.mainThreadId = win32api.GetCurrentThreadId()
         self.idleHandlerSet = 0
         self.SetIdleHandler()
@@ -520,7 +520,7 @@ def QueueFlush(self, max=None):
             self.currentView.dowrite("".join(items))
         return rc
 
-    def HandleOutput(self, message):
+    def HandleOutput(self, message: str):
         # 		debug("QueueOutput on thread %d, flags %d with '%s'...\n" % (win32api.GetCurrentThreadId(), self.writeQueueing, message ))
         self.outputQueue.put(message)
         if win32api.GetCurrentThreadId() != self.mainThreadId:
diff --git a/pythonwin/pywin/scintilla/config.py b/pythonwin/pywin/scintilla/config.py
index 45c2a095c0..3a4589c538 100644
--- a/pythonwin/pywin/scintilla/config.py
+++ b/pythonwin/pywin/scintilla/config.py
@@ -8,6 +8,8 @@
 # .py file, and put the config info in a docstring.  Then
 # pass a CStringIO file (rather than a filename) to the
 # config manager.
+from __future__ import annotations
+
 import glob
 import importlib.util
 import marshal
@@ -35,7 +37,7 @@ def trace(*args):
 compiled_config_version = 3
 
 
-def split_line(line, lineno):
+def split_line(line: str, lineno: int):
     comment_pos = line.find("#")
     if comment_pos >= 0:
         line = line[:comment_pos]
@@ -269,7 +271,7 @@ def _save_data(self, name, data):
         return data
 
     def _load_general(self, sub_section, fp, lineno):
-        map = {}
+        map: dict[str, list[str | None]] = {}
         while 1:
             line, lineno, bBreak = self._readline(fp, lineno)
             if bBreak:
diff --git a/pythonwin/pywin/scintilla/view.py b/pythonwin/pywin/scintilla/view.py
index bc816808fa..0081e9f9aa 100644
--- a/pythonwin/pywin/scintilla/view.py
+++ b/pythonwin/pywin/scintilla/view.py
@@ -667,8 +667,8 @@ def _GetWordSplit(self, pos=-1, bAllowCalls=0):
         if pos == -1:
             pos = self.GetSel()[0] - 1  # Character before current one
         limit = self.GetTextLength()
-        before = []
-        after = []
+        before: list[str] = []
+        after: list[str] = []
         index = pos - 1
         wordbreaks_use = wordbreaks
         if bAllowCalls:
diff --git a/win32/Lib/win32pdhquery.py b/win32/Lib/win32pdhquery.py
index e356f89142..ec1a9a2cca 100644
--- a/win32/Lib/win32pdhquery.py
+++ b/win32/Lib/win32pdhquery.py
@@ -124,10 +124,12 @@
 """
 
 # Feb 12, 98 - MH added "rawaddcounter" so caller can get exception details.
+from __future__ import annotations
 
 import _thread
 import copy
 import time
+from itertools import chain
 
 import win32api
 import win32pdh
@@ -445,14 +447,11 @@ def getinstpaths(
                 cur += 1
         except IndexError:  # if we went over the end
             pass
-        paths = []
-        for ind in range(len(temp)):
-            # can this raise an error?
-            paths.append(
-                win32pdh.MakeCounterPath(
-                    (machine, "Process", object, None, ind, counter)
-                )
-            )
+        paths = [
+            win32pdh.MakeCounterPath((machine, "Process", object, None, ind, counter))
+            for ind in range(len(temp))
+        ]
+
         return paths  # should also return the number of elements for naming purposes
 
     def open(self, *args, **namedargs):
@@ -467,9 +466,11 @@ def open(self, *args, **namedargs):
         # do all the normal opening stuff, self._base is now the query object
         BaseQuery.open(*(self,) + args, **namedargs)
         # should rewrite getinstpaths to take a single tuple
-        paths = []
-        for tup in self.volatilecounters:
-            paths[len(paths) :] = self.getinstpaths(*tup)
+        paths = list(
+            chain.from_iterable(
+                self.getinstpaths(*tup) for tup in self.volatilecounters
+            )
+        )
         for path in paths:
             try:
                 self.counters.append(win32pdh.AddCounter(self._base, path))
diff --git a/win32/Lib/win32pdhutil.py b/win32/Lib/win32pdhutil.py
index 839cb39291..72a0c99826 100644
--- a/win32/Lib/win32pdhutil.py
+++ b/win32/Lib/win32pdhutil.py
@@ -100,7 +100,7 @@ def FindPerformanceAttributesByName(
     instanceName = instanceName.lower()
     items, instances = win32pdh.EnumObjectItems(None, None, object, -1)
     # Track multiple instances.
-    instance_dict = {}
+    instance_dict: dict[str, int] = {}
     for instance in instances:
         try:
             instance_dict[instance] += 1
@@ -125,7 +125,7 @@ def ShowAllProcesses():
         None, None, object, win32pdh.PERF_DETAIL_WIZARD
     )
     # Need to track multiple instances of the same name.
-    instance_dict = {}
+    instance_dict: dict[str, int] = {}
     for instance in instances:
         try:
             instance_dict[instance] += 1
diff --git a/win32/Lib/win32serviceutil.py b/win32/Lib/win32serviceutil.py
index 3276bc61b0..f93db3e5f2 100644
--- a/win32/Lib/win32serviceutil.py
+++ b/win32/Lib/win32serviceutil.py
@@ -5,6 +5,7 @@
 # (which is win32service.error, pywintypes.error, etc)
 # when things go wrong - eg, not enough permissions to hit the
 # registry etc.
+from __future__ import annotations
 
 import importlib.machinery
 import os
@@ -440,8 +441,8 @@ def ControlService(serviceName, code, machine=None):
     return status
 
 
-def __FindSvcDeps(findName):
-    dict = {}
+def __FindSvcDeps(findName: str):
+    deps_dict: dict[str, list[str]] = {}
     k = win32api.RegOpenKey(
         win32con.HKEY_LOCAL_MACHINE, "SYSTEM\\CurrentControlSet\\Services"
     )
@@ -459,19 +460,19 @@ def __FindSvcDeps(findName):
             deps = ()
         for dep in deps:
             dep = dep.lower()
-            dep_on = dict.get(dep, [])
+            dep_on = deps_dict.get(dep, [])
             dep_on.append(svc)
-            dict[dep] = dep_on
+            deps_dict[dep] = dep_on
 
-    return __ResolveDeps(findName, dict)
+    return __ResolveDeps(findName, deps_dict)
 
 
-def __ResolveDeps(findName, dict):
-    items = dict.get(findName.lower(), [])
-    retList = []
+def __ResolveDeps(findName: str, deps_dict: dict[str, list[str]]):
+    items = deps_dict.get(findName.lower(), [])
+    retList: list[str] = []
     for svc in items:
         retList.insert(0, svc)
-        retList = __ResolveDeps(svc, dict) + retList
+        retList = __ResolveDeps(svc, deps_dict) + retList
     return retList