diff --git a/src/compiler/transformers/classFields.ts b/src/compiler/transformers/classFields.ts
index 01e3d7c7896a8..69fa41b207187 100644
--- a/src/compiler/transformers/classFields.ts
+++ b/src/compiler/transformers/classFields.ts
@@ -579,7 +579,7 @@ namespace ts {
         }
 
         function isPropertyDeclarationThatRequiresConstructorStatement(member: ClassElement): member is PropertyDeclaration {
-            if (!isPropertyDeclaration(member) || hasStaticModifier(member)) {
+            if (!isPropertyDeclaration(member) || hasStaticModifier(member) || hasSyntacticModifier(getOriginalNode(member), ModifierFlags.Abstract)) {
                 return false;
             }
             if (context.getCompilerOptions().useDefineForClassFields) {
@@ -779,6 +779,9 @@ namespace ts {
             }
 
             const propertyOriginalNode = getOriginalNode(property);
+            if (hasSyntacticModifier(propertyOriginalNode, ModifierFlags.Abstract)) {
+                return undefined;
+            }
             const initializer = property.initializer || emitAssignment ? visitNode(property.initializer, visitor, isExpression) ?? factory.createVoidZero()
                 : isParameterPropertyDeclaration(propertyOriginalNode, propertyOriginalNode.parent) && isIdentifier(propertyName) ? propertyName
                 : factory.createVoidZero();
diff --git a/src/compiler/transformers/ts.ts b/src/compiler/transformers/ts.ts
index 3e2e789259915..98fff3625ab06 100644
--- a/src/compiler/transformers/ts.ts
+++ b/src/compiler/transformers/ts.ts
@@ -1900,7 +1900,7 @@ namespace ts {
         }
 
         function visitPropertyDeclaration(node: PropertyDeclaration) {
-            if (node.flags & NodeFlags.Ambient) {
+            if (node.flags & NodeFlags.Ambient || hasSyntacticModifier(node, ModifierFlags.Abstract)) {
                 return undefined;
             }
             const updated = factory.updatePropertyDeclaration(
diff --git a/tests/baselines/reference/abstractProperty(target=es2015).js b/tests/baselines/reference/abstractProperty(target=es2015).js
new file mode 100644
index 0000000000000..37eb53fd7cb0c
--- /dev/null
+++ b/tests/baselines/reference/abstractProperty(target=es2015).js
@@ -0,0 +1,38 @@
+//// [abstractProperty.ts]
+abstract class A {
+    protected abstract x: string;
+    public foo() {
+        console.log(this.x);
+    }
+}
+
+class B extends A {
+    protected x = 'B.x';
+}
+
+class C extends A {
+    protected get x() { return 'C.x' };
+}
+
+
+//// [abstractProperty.js]
+class A {
+    foo() {
+        console.log(this.x);
+    }
+}
+class B extends A {
+    constructor() {
+        super(...arguments);
+        Object.defineProperty(this, "x", {
+            enumerable: true,
+            configurable: true,
+            writable: true,
+            value: 'B.x'
+        });
+    }
+}
+class C extends A {
+    get x() { return 'C.x'; }
+    ;
+}
diff --git a/tests/baselines/reference/abstractProperty(target=es2015).symbols b/tests/baselines/reference/abstractProperty(target=es2015).symbols
new file mode 100644
index 0000000000000..1f2f0b97570ac
--- /dev/null
+++ b/tests/baselines/reference/abstractProperty(target=es2015).symbols
@@ -0,0 +1,36 @@
+=== tests/cases/conformance/classes/propertyMemberDeclarations/abstractProperty.ts ===
+abstract class A {
+>A : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+
+    protected abstract x: string;
+>x : Symbol(A.x, Decl(abstractProperty.ts, 0, 18))
+
+    public foo() {
+>foo : Symbol(A.foo, Decl(abstractProperty.ts, 1, 33))
+
+        console.log(this.x);
+>console.log : Symbol(Console.log, Decl(lib.dom.d.ts, --, --))
+>console : Symbol(console, Decl(lib.dom.d.ts, --, --))
+>log : Symbol(Console.log, Decl(lib.dom.d.ts, --, --))
+>this.x : Symbol(A.x, Decl(abstractProperty.ts, 0, 18))
+>this : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+>x : Symbol(A.x, Decl(abstractProperty.ts, 0, 18))
+    }
+}
+
+class B extends A {
+>B : Symbol(B, Decl(abstractProperty.ts, 5, 1))
+>A : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+
+    protected x = 'B.x';
+>x : Symbol(B.x, Decl(abstractProperty.ts, 7, 19))
+}
+
+class C extends A {
+>C : Symbol(C, Decl(abstractProperty.ts, 9, 1))
+>A : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+
+    protected get x() { return 'C.x' };
+>x : Symbol(C.x, Decl(abstractProperty.ts, 11, 19))
+}
+
diff --git a/tests/baselines/reference/abstractProperty(target=es2015).types b/tests/baselines/reference/abstractProperty(target=es2015).types
new file mode 100644
index 0000000000000..557c5833185dc
--- /dev/null
+++ b/tests/baselines/reference/abstractProperty(target=es2015).types
@@ -0,0 +1,39 @@
+=== tests/cases/conformance/classes/propertyMemberDeclarations/abstractProperty.ts ===
+abstract class A {
+>A : A
+
+    protected abstract x: string;
+>x : string
+
+    public foo() {
+>foo : () => void
+
+        console.log(this.x);
+>console.log(this.x) : void
+>console.log : (...data: any[]) => void
+>console : Console
+>log : (...data: any[]) => void
+>this.x : string
+>this : this
+>x : string
+    }
+}
+
+class B extends A {
+>B : B
+>A : A
+
+    protected x = 'B.x';
+>x : string
+>'B.x' : "B.x"
+}
+
+class C extends A {
+>C : C
+>A : A
+
+    protected get x() { return 'C.x' };
+>x : string
+>'C.x' : "C.x"
+}
+
diff --git a/tests/baselines/reference/abstractProperty(target=esnext).js b/tests/baselines/reference/abstractProperty(target=esnext).js
new file mode 100644
index 0000000000000..dd2f6822080d9
--- /dev/null
+++ b/tests/baselines/reference/abstractProperty(target=esnext).js
@@ -0,0 +1,30 @@
+//// [abstractProperty.ts]
+abstract class A {
+    protected abstract x: string;
+    public foo() {
+        console.log(this.x);
+    }
+}
+
+class B extends A {
+    protected x = 'B.x';
+}
+
+class C extends A {
+    protected get x() { return 'C.x' };
+}
+
+
+//// [abstractProperty.js]
+class A {
+    foo() {
+        console.log(this.x);
+    }
+}
+class B extends A {
+    x = 'B.x';
+}
+class C extends A {
+    get x() { return 'C.x'; }
+    ;
+}
diff --git a/tests/baselines/reference/abstractProperty(target=esnext).symbols b/tests/baselines/reference/abstractProperty(target=esnext).symbols
new file mode 100644
index 0000000000000..1f2f0b97570ac
--- /dev/null
+++ b/tests/baselines/reference/abstractProperty(target=esnext).symbols
@@ -0,0 +1,36 @@
+=== tests/cases/conformance/classes/propertyMemberDeclarations/abstractProperty.ts ===
+abstract class A {
+>A : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+
+    protected abstract x: string;
+>x : Symbol(A.x, Decl(abstractProperty.ts, 0, 18))
+
+    public foo() {
+>foo : Symbol(A.foo, Decl(abstractProperty.ts, 1, 33))
+
+        console.log(this.x);
+>console.log : Symbol(Console.log, Decl(lib.dom.d.ts, --, --))
+>console : Symbol(console, Decl(lib.dom.d.ts, --, --))
+>log : Symbol(Console.log, Decl(lib.dom.d.ts, --, --))
+>this.x : Symbol(A.x, Decl(abstractProperty.ts, 0, 18))
+>this : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+>x : Symbol(A.x, Decl(abstractProperty.ts, 0, 18))
+    }
+}
+
+class B extends A {
+>B : Symbol(B, Decl(abstractProperty.ts, 5, 1))
+>A : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+
+    protected x = 'B.x';
+>x : Symbol(B.x, Decl(abstractProperty.ts, 7, 19))
+}
+
+class C extends A {
+>C : Symbol(C, Decl(abstractProperty.ts, 9, 1))
+>A : Symbol(A, Decl(abstractProperty.ts, 0, 0))
+
+    protected get x() { return 'C.x' };
+>x : Symbol(C.x, Decl(abstractProperty.ts, 11, 19))
+}
+
diff --git a/tests/baselines/reference/abstractProperty(target=esnext).types b/tests/baselines/reference/abstractProperty(target=esnext).types
new file mode 100644
index 0000000000000..557c5833185dc
--- /dev/null
+++ b/tests/baselines/reference/abstractProperty(target=esnext).types
@@ -0,0 +1,39 @@
+=== tests/cases/conformance/classes/propertyMemberDeclarations/abstractProperty.ts ===
+abstract class A {
+>A : A
+
+    protected abstract x: string;
+>x : string
+
+    public foo() {
+>foo : () => void
+
+        console.log(this.x);
+>console.log(this.x) : void
+>console.log : (...data: any[]) => void
+>console : Console
+>log : (...data: any[]) => void
+>this.x : string
+>this : this
+>x : string
+    }
+}
+
+class B extends A {
+>B : B
+>A : A
+
+    protected x = 'B.x';
+>x : string
+>'B.x' : "B.x"
+}
+
+class C extends A {
+>C : C
+>A : A
+
+    protected get x() { return 'C.x' };
+>x : string
+>'C.x' : "C.x"
+}
+
diff --git a/tests/baselines/reference/accessorsOverrideProperty7.js b/tests/baselines/reference/accessorsOverrideProperty7.js
index 206f8611b7fa1..7264bf45e5fc8 100644
--- a/tests/baselines/reference/accessorsOverrideProperty7.js
+++ b/tests/baselines/reference/accessorsOverrideProperty7.js
@@ -23,12 +23,6 @@ var __extends = (this && this.__extends) || (function () {
 })();
 var A = /** @class */ (function () {
     function A() {
-        Object.defineProperty(this, "p", {
-            enumerable: true,
-            configurable: true,
-            writable: true,
-            value: 'yep'
-        });
     }
     return A;
 }());
diff --git a/tests/baselines/reference/privateNamesIncompatibleModifiers.js b/tests/baselines/reference/privateNamesIncompatibleModifiers.js
index 48695a4604fbc..f6e731d371d88 100644
--- a/tests/baselines/reference/privateNamesIncompatibleModifiers.js
+++ b/tests/baselines/reference/privateNamesIncompatibleModifiers.js
@@ -14,7 +14,7 @@ abstract class B {
 
 //// [privateNamesIncompatibleModifiers.js]
 "use strict";
-var _foo, _bar, _baz, _qux, _quux;
+var _foo, _bar, _baz, _qux;
 class A {
     constructor() {
         _foo.set(this, 3); // Error
@@ -25,8 +25,4 @@ class A {
 }
 _foo = new WeakMap(), _bar = new WeakMap(), _baz = new WeakMap(), _qux = new WeakMap();
 class B {
-    constructor() {
-        _quux.set(this, 3); // Error
-    }
 }
-_quux = new WeakMap();
diff --git a/tests/cases/conformance/classes/propertyMemberDeclarations/abstractProperty.ts b/tests/cases/conformance/classes/propertyMemberDeclarations/abstractProperty.ts
new file mode 100644
index 0000000000000..5f7266c0ea70d
--- /dev/null
+++ b/tests/cases/conformance/classes/propertyMemberDeclarations/abstractProperty.ts
@@ -0,0 +1,16 @@
+// @target: es2015,esnext
+// @useDefineForClassFields: true
+abstract class A {
+    protected abstract x: string;
+    public foo() {
+        console.log(this.x);
+    }
+}
+
+class B extends A {
+    protected x = 'B.x';
+}
+
+class C extends A {
+    protected get x() { return 'C.x' };
+}