diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index f27a6058006e5..f13f604ddcd2b 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -13435,6 +13435,26 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
         return emptyArray;
     }
 
+    function getSpreadIndexInfos(left: Type, right: Type): IndexInfo[] {
+        const rightInfos = getIndexInfosOfType(right);
+        if (!rightInfos.length) return emptyArray;
+        const leftInfos = getIndexInfosOfType(left);
+        const leftProperties = getPropertiesOfType(left);
+        const result: IndexInfo[] = [];
+        for (const rightInfo of rightInfos) {
+            const indexType = rightInfo.keyType;
+            const leftInfo = findIndexInfo(leftInfos, indexType);
+            const types = leftInfo ? [leftInfo.type, rightInfo.type] : [rightInfo.type];
+            for (const prop of leftProperties) {
+                if (isApplicableIndexType(getNameTypeOfPropertyName(prop.escapedName), indexType)) {
+                    types.push(getTypeOfSymbol(prop));
+                }
+            }
+            result.push(createIndexInfo(indexType, getUnionType(types), leftInfo && leftInfo.isReadonly || rightInfo.isReadonly));
+        }
+        return result;
+    }
+
     function resolveUnionTypeMembers(type: UnionType) {
         // The members and properties collections are empty for union types. To get all properties of a union
         // type use getPropertiesOfType (only the language service uses this).
@@ -14888,7 +14908,11 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
     }
 
     function getApplicableIndexInfoForName(type: Type, name: __String): IndexInfo | undefined {
-        return getApplicableIndexInfo(type, isLateBoundName(name) ? esSymbolType : getStringLiteralType(unescapeLeadingUnderscores(name)));
+        return getApplicableIndexInfo(type, getNameTypeOfPropertyName(name));
+    }
+
+    function getNameTypeOfPropertyName(name: __String): Type {
+        return isLateBoundName(name) ? esSymbolType : getStringLiteralType(unescapeLeadingUnderscores(name));
     }
 
     // Return list of type parameters with duplicates removed (duplicate identifier errors are generated in the actual
@@ -18793,7 +18817,7 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
 
         const members = createSymbolTable();
         const skippedPrivateMembers = new Set<__String>();
-        const indexInfos = left === emptyObjectType ? getIndexInfosOfType(right) : getUnionIndexInfos([left, right]);
+        const indexInfos = left === emptyObjectType ? getIndexInfosOfType(right) : getSpreadIndexInfos(left, right);
 
         for (const rightProp of getPropertiesOfType(right)) {
             if (getDeclarationModifierFlagsFromSymbol(rightProp) & (ModifierFlags.Private | ModifierFlags.Protected)) {
diff --git a/tests/baselines/reference/constAssertions.js b/tests/baselines/reference/constAssertions.js
index 3173e2bf92ae3..8da3b3e5b51d0 100644
--- a/tests/baselines/reference/constAssertions.js
+++ b/tests/baselines/reference/constAssertions.js
@@ -258,6 +258,7 @@ declare let o2: {
     readonly d: () => void;
 };
 declare let o3: {
+    readonly [x: string]: 10 | 1 | 2 | 3 | 20 | (() => void) | 4;
     readonly a: 1;
     readonly b: 2;
     readonly c: 3;
diff --git a/tests/baselines/reference/constAssertions.types b/tests/baselines/reference/constAssertions.types
index 0668c0235aa0e..a042eb1746686 100644
--- a/tests/baselines/reference/constAssertions.types
+++ b/tests/baselines/reference/constAssertions.types
@@ -202,9 +202,9 @@ let o2 = { a: 1, 'b': 2, ['c']: 3, d() {}, ['e' + '']: 4 } as const;
 >4 : 4
 
 let o3 = { ...o1, ...o2 } as const;
->o3 : { readonly a: 1; readonly b: 2; readonly c: 3; readonly d: () => void; readonly x: 10; readonly y: 20; }
->{ ...o1, ...o2 } as const : { readonly a: 1; readonly b: 2; readonly c: 3; readonly d: () => void; readonly x: 10; readonly y: 20; }
->{ ...o1, ...o2 } : { readonly a: 1; readonly b: 2; readonly c: 3; readonly d: () => void; readonly x: 10; readonly y: 20; }
+>o3 : { readonly [x: string]: 10 | 1 | 2 | 3 | 20 | (() => void) | 4; readonly a: 1; readonly b: 2; readonly c: 3; readonly d: () => void; readonly x: 10; readonly y: 20; }
+>{ ...o1, ...o2 } as const : { readonly [x: string]: 10 | 1 | 2 | 3 | 20 | (() => void) | 4; readonly a: 1; readonly b: 2; readonly c: 3; readonly d: () => void; readonly x: 10; readonly y: 20; }
+>{ ...o1, ...o2 } : { readonly [x: string]: 10 | 1 | 2 | 3 | 20 | (() => void) | 4; readonly a: 1; readonly b: 2; readonly c: 3; readonly d: () => void; readonly x: 10; readonly y: 20; }
 >o1 : { readonly x: 10; readonly y: 20; }
 >o2 : { readonly [x: string]: 1 | 2 | 3 | (() => void) | 4; readonly a: 1; readonly b: 2; readonly c: 3; readonly d: () => void; }
 
diff --git a/tests/baselines/reference/objectSpreadComputedProperty.types b/tests/baselines/reference/objectSpreadComputedProperty.types
index ce61004aa04c6..16bd8a6de0a68 100644
--- a/tests/baselines/reference/objectSpreadComputedProperty.types
+++ b/tests/baselines/reference/objectSpreadComputedProperty.types
@@ -17,24 +17,24 @@ function f() {
 >a : any
 
     const o1 = { ...{}, [n]: n };
->o1 : {}
->{ ...{}, [n]: n } : {}
+>o1 : { [x: number]: number; }
+>{ ...{}, [n]: n } : { [x: number]: number; }
 >{} : {}
 >[n] : number
 >n : number
 >n : number
 
     const o2 = { ...{}, [a]: n };
->o2 : {}
->{ ...{}, [a]: n } : {}
+>o2 : { [x: number]: number; }
+>{ ...{}, [a]: n } : { [x: number]: number; }
 >{} : {}
 >[a] : number
 >a : any
 >n : number
 
     const o3 = { [a]: n, ...{}, [n]: n, ...{}, [m]: m };
->o3 : {}
->{ [a]: n, ...{}, [n]: n, ...{}, [m]: m } : {}
+>o3 : { [x: number]: number; }
+>{ [a]: n, ...{}, [n]: n, ...{}, [m]: m } : { [x: number]: number; }
 >[a] : number
 >a : any
 >n : number
diff --git a/tests/baselines/reference/spreadIndexSignature.js b/tests/baselines/reference/spreadIndexSignature.js
new file mode 100644
index 0000000000000..4963257e00840
--- /dev/null
+++ b/tests/baselines/reference/spreadIndexSignature.js
@@ -0,0 +1,15 @@
+//// [tests/cases/compiler/spreadIndexSignature.ts] ////
+
+//// [spreadIndexSignature.ts]
+declare const strings: Record<string, string>;
+declare const symbols: Record<symbol, string>;
+
+const o1 = { a: 1, ...strings };
+const o2 = { [Symbol.iterator]: 1, ...strings };
+const o3 = { [Symbol.iterator]: 1, ...symbols };
+
+
+//// [spreadIndexSignature.js]
+const o1 = { a: 1, ...strings };
+const o2 = { [Symbol.iterator]: 1, ...strings };
+const o3 = { [Symbol.iterator]: 1, ...symbols };
diff --git a/tests/baselines/reference/spreadIndexSignature.symbols b/tests/baselines/reference/spreadIndexSignature.symbols
new file mode 100644
index 0000000000000..9811f1f123bf5
--- /dev/null
+++ b/tests/baselines/reference/spreadIndexSignature.symbols
@@ -0,0 +1,32 @@
+//// [tests/cases/compiler/spreadIndexSignature.ts] ////
+
+=== spreadIndexSignature.ts ===
+declare const strings: Record<string, string>;
+>strings : Symbol(strings, Decl(spreadIndexSignature.ts, 0, 13))
+>Record : Symbol(Record, Decl(lib.es5.d.ts, --, --))
+
+declare const symbols: Record<symbol, string>;
+>symbols : Symbol(symbols, Decl(spreadIndexSignature.ts, 1, 13))
+>Record : Symbol(Record, Decl(lib.es5.d.ts, --, --))
+
+const o1 = { a: 1, ...strings };
+>o1 : Symbol(o1, Decl(spreadIndexSignature.ts, 3, 5))
+>a : Symbol(a, Decl(spreadIndexSignature.ts, 3, 12))
+>strings : Symbol(strings, Decl(spreadIndexSignature.ts, 0, 13))
+
+const o2 = { [Symbol.iterator]: 1, ...strings };
+>o2 : Symbol(o2, Decl(spreadIndexSignature.ts, 4, 5))
+>[Symbol.iterator] : Symbol([Symbol.iterator], Decl(spreadIndexSignature.ts, 4, 12))
+>Symbol.iterator : Symbol(SymbolConstructor.iterator, Decl(lib.es2015.iterable.d.ts, --, --))
+>Symbol : Symbol(Symbol, Decl(lib.es5.d.ts, --, --), Decl(lib.es2015.symbol.d.ts, --, --), Decl(lib.es2015.symbol.wellknown.d.ts, --, --), Decl(lib.es2019.symbol.d.ts, --, --))
+>iterator : Symbol(SymbolConstructor.iterator, Decl(lib.es2015.iterable.d.ts, --, --))
+>strings : Symbol(strings, Decl(spreadIndexSignature.ts, 0, 13))
+
+const o3 = { [Symbol.iterator]: 1, ...symbols };
+>o3 : Symbol(o3, Decl(spreadIndexSignature.ts, 5, 5))
+>[Symbol.iterator] : Symbol([Symbol.iterator], Decl(spreadIndexSignature.ts, 5, 12))
+>Symbol.iterator : Symbol(SymbolConstructor.iterator, Decl(lib.es2015.iterable.d.ts, --, --))
+>Symbol : Symbol(Symbol, Decl(lib.es5.d.ts, --, --), Decl(lib.es2015.symbol.d.ts, --, --), Decl(lib.es2015.symbol.wellknown.d.ts, --, --), Decl(lib.es2019.symbol.d.ts, --, --))
+>iterator : Symbol(SymbolConstructor.iterator, Decl(lib.es2015.iterable.d.ts, --, --))
+>symbols : Symbol(symbols, Decl(spreadIndexSignature.ts, 1, 13))
+
diff --git a/tests/baselines/reference/spreadIndexSignature.types b/tests/baselines/reference/spreadIndexSignature.types
new file mode 100644
index 0000000000000..cd616ab319354
--- /dev/null
+++ b/tests/baselines/reference/spreadIndexSignature.types
@@ -0,0 +1,36 @@
+//// [tests/cases/compiler/spreadIndexSignature.ts] ////
+
+=== spreadIndexSignature.ts ===
+declare const strings: Record<string, string>;
+>strings : Record<string, string>
+
+declare const symbols: Record<symbol, string>;
+>symbols : Record<symbol, string>
+
+const o1 = { a: 1, ...strings };
+>o1 : { [x: string]: string | number; a: number; }
+>{ a: 1, ...strings } : { [x: string]: string | number; a: number; }
+>a : number
+>1 : 1
+>strings : Record<string, string>
+
+const o2 = { [Symbol.iterator]: 1, ...strings };
+>o2 : { [x: string]: string; [Symbol.iterator]: number; }
+>{ [Symbol.iterator]: 1, ...strings } : { [x: string]: string; [Symbol.iterator]: number; }
+>[Symbol.iterator] : number
+>Symbol.iterator : unique symbol
+>Symbol : SymbolConstructor
+>iterator : unique symbol
+>1 : 1
+>strings : Record<string, string>
+
+const o3 = { [Symbol.iterator]: 1, ...symbols };
+>o3 : { [x: symbol]: string | number; [Symbol.iterator]: number; }
+>{ [Symbol.iterator]: 1, ...symbols } : { [x: symbol]: string | number; [Symbol.iterator]: number; }
+>[Symbol.iterator] : number
+>Symbol.iterator : unique symbol
+>Symbol : SymbolConstructor
+>iterator : unique symbol
+>1 : 1
+>symbols : Record<symbol, string>
+
diff --git a/tests/baselines/reference/useBeforeDeclaration_propertyAssignment.types b/tests/baselines/reference/useBeforeDeclaration_propertyAssignment.types
index a6c6e1faceb89..15079f94f2c24 100644
--- a/tests/baselines/reference/useBeforeDeclaration_propertyAssignment.types
+++ b/tests/baselines/reference/useBeforeDeclaration_propertyAssignment.types
@@ -5,8 +5,8 @@ export class C {
 >C : C
 
     public a =  { b: this.b, ...this.c, [this.b]: `${this.c}`};
->a : { c: number; b: number; }
->{ b: this.b, ...this.c, [this.b]: `${this.c}`} : { c: number; b: number; }
+>a : { [x: number]: string; c: number; b: number; }
+>{ b: this.b, ...this.c, [this.b]: `${this.c}`} : { [x: number]: string; c: number; b: number; }
 >b : number
 >this.b : number
 >this : this
diff --git a/tests/cases/compiler/spreadIndexSignature.ts b/tests/cases/compiler/spreadIndexSignature.ts
new file mode 100644
index 0000000000000..75215d6942ef7
--- /dev/null
+++ b/tests/cases/compiler/spreadIndexSignature.ts
@@ -0,0 +1,8 @@
+// @target: esnext
+
+declare const strings: Record<string, string>;
+declare const symbols: Record<symbol, string>;
+
+const o1 = { a: 1, ...strings };
+const o2 = { [Symbol.iterator]: 1, ...strings };
+const o3 = { [Symbol.iterator]: 1, ...symbols };