diff --git a/pandas/core/algorithms.py b/pandas/core/algorithms.py
index d6cc9cf1b9bac..1988753de3d01 100644
--- a/pandas/core/algorithms.py
+++ b/pandas/core/algorithms.py
@@ -462,13 +462,13 @@ def isin(comps: AnyArrayLike, values: AnyArrayLike) -> npt.NDArray[np.bool_]:
         )
 
     if not isinstance(values, (ABCIndex, ABCSeries, ABCExtensionArray, np.ndarray)):
-        orig_values = values
-        values = _ensure_arraylike(list(values))
+        orig_values = list(values)
+        values = _ensure_arraylike(orig_values)
 
         if is_numeric_dtype(values) and not is_signed_integer_dtype(comps):
             # GH#46485 Use object to avoid upcast to float64 later
             # TODO: Share with _find_common_type_compat
-            values = construct_1d_object_array_from_listlike(list(orig_values))
+            values = construct_1d_object_array_from_listlike(orig_values)
 
     elif isinstance(values, ABCMultiIndex):
         # Avoid raising in extract_array