diff --git a/Modules/_ctypes/callproc.c b/Modules/_ctypes/callproc.c
index 3b11cd7f58ce4b..6c8ac813ed6194 100644
--- a/Modules/_ctypes/callproc.c
+++ b/Modules/_ctypes/callproc.c
@@ -1139,8 +1139,7 @@ GetComError(HRESULT errcode, GUID *riid, IUnknown *pIunk)
 }
 #endif
 
-#if (defined(__x86_64__) && (defined(__MINGW64__) || defined(__CYGWIN__))) || \
-    defined(__aarch64__) || defined(__riscv)
+#if (defined(__x86_64__) && (defined(__MINGW64__) || defined(__CYGWIN__)))
 #define CTYPES_PASS_BY_REF_HACK
 #define POW2(x) (((x & ~(x - 1)) == x) ? x : 0)
 #define IS_PASS_BY_REF(x) (x > 8 || !POW2(x))