diff --git a/Mac/BuildScript/build-installer.py b/Mac/BuildScript/build-installer.py
index c54de880c20360..58700204a9a5f3 100755
--- a/Mac/BuildScript/build-installer.py
+++ b/Mac/BuildScript/build-installer.py
@@ -359,16 +359,16 @@ def library_recipes():
                   ),
           ),
           dict(
-              name="SQLite 3.42.0",
-              url="https://sqlite.org/2023/sqlite-autoconf-3420000.tar.gz",
-              checksum="0c5a92bc51cf07cae45b4a1e94653dea",
-              extra_cflags=('-Os '
-                            '-DSQLITE_ENABLE_FTS5 '
-                            '-DSQLITE_ENABLE_FTS4 '
-                            '-DSQLITE_ENABLE_FTS3_PARENTHESIS '
-                            '-DSQLITE_ENABLE_RTREE '
-                            '-DSQLITE_OMIT_AUTOINIT '
-                            '-DSQLITE_TCL=0 '
+              name="SQLite 3.43.1",
+              url="https://sqlite.org/2023/sqlite-autoconf-3430100.tar.gz",
+              checksum="77e61befe9c3298da0504f87772a24b0",
+	          extra_cflags=('-Os '
+                '-DSQLITE_ENABLE_FTS5 '
+                '-DSQLITE_ENABLE_FTS4 '
+                '-DSQLITE_ENABLE_FTS3_PARENTHESIS '
+                '-DSQLITE_ENABLE_RTREE '
+                '-DSQLITE_OMIT_AUTOINIT '
+                '-DSQLITE_TCL=0 '
                             ),
               configure_pre=[
                   '--enable-threadsafe',
diff --git a/Misc/NEWS.d/next/macOS/2023-10-04-23-38-24.gh-issue-109286.1ZLMaq.rst b/Misc/NEWS.d/next/macOS/2023-10-04-23-38-24.gh-issue-109286.1ZLMaq.rst
new file mode 100644
index 00000000000000..7d47fb30e3166f
--- /dev/null
+++ b/Misc/NEWS.d/next/macOS/2023-10-04-23-38-24.gh-issue-109286.1ZLMaq.rst
@@ -0,0 +1 @@
+Upgraded macOS SQLite installer to 3.43.1
diff --git a/PCbuild/get_externals.bat b/PCbuild/get_externals.bat
index fc43ce2b1835d0..94437f054d788c 100644
--- a/PCbuild/get_externals.bat
+++ b/PCbuild/get_externals.bat
@@ -54,7 +54,7 @@ set libraries=
 set libraries=%libraries%                                       bzip2-1.0.8
 if NOT "%IncludeLibffiSrc%"=="false" set libraries=%libraries%  libffi-3.4.4
 if NOT "%IncludeSSLSrc%"=="false" set libraries=%libraries%     openssl-3.0.11
-set libraries=%libraries%                                       sqlite-3.42.0.0
+set libraries=%libraries%                                       sqlite-3.43.1.0
 if NOT "%IncludeTkinterSrc%"=="false" set libraries=%libraries% tcl-core-8.6.13.0
 if NOT "%IncludeTkinterSrc%"=="false" set libraries=%libraries% tk-8.6.13.0
 set libraries=%libraries%                                       xz-5.2.5
diff --git a/PCbuild/python.props b/PCbuild/python.props
index 35c6e92be45dc9..496bc3dd4cf794 100644
--- a/PCbuild/python.props
+++ b/PCbuild/python.props
@@ -68,7 +68,7 @@
   <Import Project="$(ExternalProps)" Condition="$(ExternalProps) != '' and Exists('$(ExternalProps)')" />
 
   <PropertyGroup>
-    <sqlite3Dir Condition="$(sqlite3Dir) == ''">$(ExternalsDir)sqlite-3.42.0.0\</sqlite3Dir>
+    <sqlite3Dir Condition="$(sqlite3Dir) == ''">$(ExternalsDir)sqlite-3.43.1.0\</sqlite3Dir>
     <bz2Dir Condition="$(bz2Dir) == ''">$(ExternalsDir)bzip2-1.0.8\</bz2Dir>
     <lzmaDir Condition="$(lzmaDir) == ''">$(ExternalsDir)xz-5.2.5\</lzmaDir>
     <libffiDir Condition="$(libffiDir) == ''">$(ExternalsDir)libffi-3.4.4\</libffiDir>
diff --git a/PCbuild/readme.txt b/PCbuild/readme.txt
index 98b37014907604..175ce918ac20f6 100644
--- a/PCbuild/readme.txt
+++ b/PCbuild/readme.txt
@@ -189,7 +189,7 @@ _ssl
     again when building.
 
 _sqlite3
-    Wraps SQLite 3.42.0, which is itself built by sqlite3.vcxproj
+    Wraps SQLite 3.43.1, which is itself built by sqlite3.vcxproj
     Homepage:
         https://www.sqlite.org/
 _tkinter