diff --git a/Lib/test/test_sys_settrace.py b/Lib/test/test_sys_settrace.py
index 3540192b5bb5bb..e97e122534a2f3 100644
--- a/Lib/test/test_sys_settrace.py
+++ b/Lib/test/test_sys_settrace.py
@@ -1952,6 +1952,40 @@ def test_jump_simple_backwards(output):
         output.append(1)
         output.append(2)
 
+    @jump_test(1, 4, [5])
+    def test_jump_is_none_forwards(output):
+        x = None
+        if x is None:
+            output.append(3)
+        else:
+            output.append(5)
+
+    @jump_test(6, 5, [3, 5, 6])
+    def test_jump_is_none_backwards(output):
+        x = None
+        if x is None:
+            output.append(3)
+        else:
+            output.append(5)
+        output.append(6)
+
+    @jump_test(1, 4, [5])
+    def test_jump_is_not_none_forwards(output):
+        x = None
+        if x is not None:
+            output.append(3)
+        else:
+            output.append(5)
+
+    @jump_test(6, 5, [5, 5, 6])
+    def test_jump_is_not_none_backwards(output):
+        x = None
+        if x is not None:
+            output.append(3)
+        else:
+            output.append(5)
+        output.append(6)
+
     @jump_test(3, 5, [2, 5])
     def test_jump_out_of_block_forwards(output):
         for i in 1, 2:
diff --git a/Misc/ACKS b/Misc/ACKS
index 6eff2cc1f19e28..7efa01db59e7ea 100644
--- a/Misc/ACKS
+++ b/Misc/ACKS
@@ -1324,6 +1324,7 @@ Michele Orrù
 Tomáš Orsava
 Oleg Oshmyan
 Denis Osipov
+Savannah Ostrowski
 Denis S. Otkidach
 Peter Otten
 Michael Otteneder
diff --git a/Misc/NEWS.d/next/Core and Builtins/2023-10-23-22-11-09.gh-issue-94438.y2pITu.rst b/Misc/NEWS.d/next/Core and Builtins/2023-10-23-22-11-09.gh-issue-94438.y2pITu.rst
new file mode 100644
index 00000000000000..b6e147a48a8cd8
--- /dev/null
+++ b/Misc/NEWS.d/next/Core and Builtins/2023-10-23-22-11-09.gh-issue-94438.y2pITu.rst	
@@ -0,0 +1 @@
+Fix a regression that prevented jumping across ``is None`` and ``is not None`` when debugging. Patch by Savannah Ostrowski.
diff --git a/Objects/frameobject.c b/Objects/frameobject.c
index 425749d14cf014..c95e8711880517 100644
--- a/Objects/frameobject.c
+++ b/Objects/frameobject.c
@@ -315,19 +315,27 @@ mark_stacks(PyCodeObject *code_obj, int len)
                 case POP_JUMP_BACKWARD_IF_FALSE:
                 case POP_JUMP_FORWARD_IF_TRUE:
                 case POP_JUMP_BACKWARD_IF_TRUE:
+                case POP_JUMP_FORWARD_IF_NONE:
+                case POP_JUMP_BACKWARD_IF_NONE:
+                case POP_JUMP_FORWARD_IF_NOT_NONE:
+                case POP_JUMP_BACKWARD_IF_NOT_NONE:
                 {
                     int64_t target_stack;
                     int j = get_arg(code, i);
                     if (opcode == POP_JUMP_FORWARD_IF_FALSE ||
                         opcode == POP_JUMP_FORWARD_IF_TRUE ||
                         opcode == JUMP_IF_FALSE_OR_POP ||
-                        opcode == JUMP_IF_TRUE_OR_POP)
+                        opcode == JUMP_IF_TRUE_OR_POP ||
+                        opcode == POP_JUMP_FORWARD_IF_NONE ||
+                        opcode == POP_JUMP_FORWARD_IF_NOT_NONE)
                     {
                         j += i + 1;
                     }
                     else {
                         assert(opcode == POP_JUMP_BACKWARD_IF_FALSE ||
-                               opcode == POP_JUMP_BACKWARD_IF_TRUE);
+                               opcode == POP_JUMP_BACKWARD_IF_TRUE  ||
+                               opcode == POP_JUMP_BACKWARD_IF_NONE ||
+                               opcode == POP_JUMP_BACKWARD_IF_NOT_NONE);
                         j = i + 1 - j;
                     }
                     assert(j < len);