diff --git a/src/doc/unstable-book/src/library-features/asm.md b/src/doc/unstable-book/src/library-features/asm.md
index 0b68991fce2a1..ea560a6d70915 100644
--- a/src/doc/unstable-book/src/library-features/asm.md
+++ b/src/doc/unstable-book/src/library-features/asm.md
@@ -468,12 +468,17 @@ Here is the list of currently supported register classes:
 | ARM | `qreg` | `q[0-15]` | `w` |
 | ARM | `qreg_low8` | `q[0-7]` | `t` |
 | ARM | `qreg_low4` | `q[0-3]` | `x` |
+| NVPTX | `reg16` | None\* | `h` |
+| NVPTX | `reg32` | None\* | `r` |
+| NVPTX | `reg64` | None\* | `l` |
 | RISC-V | `reg` | `x1`, `x[5-7]`, `x[9-15]`, `x[16-31]` (non-RV32E) | `r` |
 | RISC-V | `freg` | `f[0-31]` | `f` |
 
 > **Note**: On x86 we treat `reg_byte` differently from `reg` because the compiler can allocate `al` and `ah` separately whereas `reg` reserves the whole register.
 >
 > Note #2: On x86-64 the high byte registers (e.g. `ah`) are only available when used as an explicit register. Specifying the `reg_byte` register class for an operand will always allocate a low byte register.
+>
+> Note #3: NVPTX doesn't have a fixed register set, so named registers are not supported.
 
 Additional register classes may be added in the future based on demand (e.g. MMX, x87, etc).
 
@@ -495,6 +500,9 @@ Each register class has constraints on which value types they can be used with.
 | ARM | `sreg` | `vfp2` | `i32`, `f32` |
 | ARM | `dreg` | `vfp2` | `i64`, `f64`, `i8x8`, `i16x4`, `i32x2`, `i64x1`, `f32x2` |
 | ARM | `qreg` | `neon` | `i8x16`, `i16x8`, `i32x4`, `i64x2`, `f32x4` |
+| NVPTX | `reg16` | None | `i8`, `i16` |
+| NVPTX | `reg32` | None | `i8`, `i16`, `i32`, `f32` |
+| NVPTX | `reg64` | None | `i8`, `i16`, `i32`, `f32`, `i64`, `f64` |
 | RISC-V32 | `reg` | None | `i8`, `i16`, `i32`, `f32` |
 | RISC-V64 | `reg` | None | `i8`, `i16`, `i32`, `f32`, `i64`, `f64` |
 | RISC-V | `freg` | `f` | `f32` |
@@ -610,6 +618,9 @@ The supported modifiers are a subset of LLVM's (and GCC's) [asm template argumen
 | ARM | `dreg` | None | `d0` | `P` |
 | ARM | `qreg` | None | `q0` | `q` |
 | ARM | `qreg` | `e` / `f` | `d0` / `d1` | `e` / `f` |
+| NVPTX | `reg16` | None | `rs0` | None |
+| NVPTX | `reg32` | None | `r0` | None |
+| NVPTX | `reg64` | None | `rd0` | None |
 | RISC-V | `reg` | None | `x1` | None |
 | RISC-V | `freg` | None | `f0` | None |
 
diff --git a/src/librustc_codegen_llvm/asm.rs b/src/librustc_codegen_llvm/asm.rs
index 8986ab322c07f..f3b46dd322a39 100644
--- a/src/librustc_codegen_llvm/asm.rs
+++ b/src/librustc_codegen_llvm/asm.rs
@@ -254,6 +254,7 @@ impl AsmBuilderMethods<'tcx> for Builder<'a, 'll, 'tcx> {
                     ]);
                 }
                 InlineAsmArch::RiscV32 | InlineAsmArch::RiscV64 => {}
+                InlineAsmArch::Nvptx64 => {}
             }
         }
         if !options.contains(InlineAsmOptions::NOMEM) {
@@ -410,6 +411,9 @@ fn reg_to_llvm(reg: InlineAsmRegOrRegClass) -> String {
             | InlineAsmRegClass::Arm(ArmInlineAsmRegClass::qreg_low4) => "x",
             InlineAsmRegClass::Arm(ArmInlineAsmRegClass::dreg)
             | InlineAsmRegClass::Arm(ArmInlineAsmRegClass::qreg) => "w",
+            InlineAsmRegClass::Nvptx(NvptxInlineAsmRegClass::reg16) => "h",
+            InlineAsmRegClass::Nvptx(NvptxInlineAsmRegClass::reg32) => "r",
+            InlineAsmRegClass::Nvptx(NvptxInlineAsmRegClass::reg64) => "l",
             InlineAsmRegClass::RiscV(RiscVInlineAsmRegClass::reg) => "r",
             InlineAsmRegClass::RiscV(RiscVInlineAsmRegClass::freg) => "f",
             InlineAsmRegClass::X86(X86InlineAsmRegClass::reg) => "r",
@@ -452,6 +456,7 @@ fn modifier_to_llvm(
                 modifier
             }
         }
+        InlineAsmRegClass::Nvptx(_) => None,
         InlineAsmRegClass::RiscV(RiscVInlineAsmRegClass::reg)
         | InlineAsmRegClass::RiscV(RiscVInlineAsmRegClass::freg) => None,
         InlineAsmRegClass::X86(X86InlineAsmRegClass::reg)
@@ -502,6 +507,9 @@ fn dummy_output_type(cx: &CodegenCx<'ll, 'tcx>, reg: InlineAsmRegClass) -> &'ll
         | InlineAsmRegClass::Arm(ArmInlineAsmRegClass::qreg_low4) => {
             cx.type_vector(cx.type_i64(), 2)
         }
+        InlineAsmRegClass::Nvptx(NvptxInlineAsmRegClass::reg16) => cx.type_i16(),
+        InlineAsmRegClass::Nvptx(NvptxInlineAsmRegClass::reg32) => cx.type_i32(),
+        InlineAsmRegClass::Nvptx(NvptxInlineAsmRegClass::reg64) => cx.type_i64(),
         InlineAsmRegClass::RiscV(RiscVInlineAsmRegClass::reg) => cx.type_i32(),
         InlineAsmRegClass::RiscV(RiscVInlineAsmRegClass::freg) => cx.type_f32(),
         InlineAsmRegClass::X86(X86InlineAsmRegClass::reg)
diff --git a/src/librustc_target/asm/mod.rs b/src/librustc_target/asm/mod.rs
index 774146a679ab8..a18a4dbd3e214 100644
--- a/src/librustc_target/asm/mod.rs
+++ b/src/librustc_target/asm/mod.rs
@@ -60,6 +60,7 @@ macro_rules! def_regs {
             #error = [$($bad_reg:literal),+] => $error:literal,
         )*
     }) => {
+        #[allow(unreachable_code)]
         #[derive(Copy, Clone, RustcEncodable, RustcDecodable, Debug, Eq, PartialEq, Hash, HashStable_Generic)]
         #[allow(non_camel_case_types)]
         pub enum $arch_reg {
@@ -102,19 +103,20 @@ macro_rules! def_regs {
         pub(super) fn fill_reg_map(
             _arch: super::InlineAsmArch,
             mut _has_feature: impl FnMut(&str) -> bool,
-            map: &mut rustc_data_structures::fx::FxHashMap<
+            _map: &mut rustc_data_structures::fx::FxHashMap<
                 super::InlineAsmRegClass,
                 rustc_data_structures::fx::FxHashSet<super::InlineAsmReg>,
             >,
         ) {
+            #[allow(unused_imports)]
             use super::{InlineAsmReg, InlineAsmRegClass};
             $(
                 if $($filter(_arch, &mut _has_feature, true).is_ok() &&)? true {
-                    if let Some(set) = map.get_mut(&InlineAsmRegClass::$arch($arch_regclass::$class)) {
+                    if let Some(set) = _map.get_mut(&InlineAsmRegClass::$arch($arch_regclass::$class)) {
                         set.insert(InlineAsmReg::$arch($arch_reg::$reg));
                     }
                     $(
-                        if let Some(set) = map.get_mut(&InlineAsmRegClass::$arch($arch_regclass::$extra_class)) {
+                        if let Some(set) = _map.get_mut(&InlineAsmRegClass::$arch($arch_regclass::$extra_class)) {
                             set.insert(InlineAsmReg::$arch($arch_reg::$reg));
                         }
                     )*
@@ -146,11 +148,13 @@ macro_rules! types {
 
 mod aarch64;
 mod arm;
+mod nvptx;
 mod riscv;
 mod x86;
 
 pub use aarch64::{AArch64InlineAsmReg, AArch64InlineAsmRegClass};
 pub use arm::{ArmInlineAsmReg, ArmInlineAsmRegClass};
+pub use nvptx::{NvptxInlineAsmReg, NvptxInlineAsmRegClass};
 pub use riscv::{RiscVInlineAsmReg, RiscVInlineAsmRegClass};
 pub use x86::{X86InlineAsmReg, X86InlineAsmRegClass};
 
@@ -162,6 +166,7 @@ pub enum InlineAsmArch {
     AArch64,
     RiscV32,
     RiscV64,
+    Nvptx64,
 }
 
 impl FromStr for InlineAsmArch {
@@ -175,6 +180,7 @@ impl FromStr for InlineAsmArch {
             "aarch64" => Ok(Self::AArch64),
             "riscv32" => Ok(Self::RiscV32),
             "riscv64" => Ok(Self::RiscV64),
+            "nvptx64" => Ok(Self::Nvptx64),
             _ => Err(()),
         }
     }
@@ -196,6 +202,7 @@ pub enum InlineAsmReg {
     Arm(ArmInlineAsmReg),
     AArch64(AArch64InlineAsmReg),
     RiscV(RiscVInlineAsmReg),
+    Nvptx(NvptxInlineAsmReg),
 }
 
 impl InlineAsmReg {
@@ -236,6 +243,9 @@ impl InlineAsmReg {
             InlineAsmArch::RiscV32 | InlineAsmArch::RiscV64 => {
                 Self::RiscV(RiscVInlineAsmReg::parse(arch, has_feature, &name)?)
             }
+            InlineAsmArch::Nvptx64 => {
+                Self::Nvptx(NvptxInlineAsmReg::parse(arch, has_feature, &name)?)
+            }
         })
     }
 
@@ -281,6 +291,7 @@ pub enum InlineAsmRegClass {
     Arm(ArmInlineAsmRegClass),
     AArch64(AArch64InlineAsmRegClass),
     RiscV(RiscVInlineAsmRegClass),
+    Nvptx(NvptxInlineAsmRegClass),
 }
 
 impl InlineAsmRegClass {
@@ -290,6 +301,7 @@ impl InlineAsmRegClass {
             Self::Arm(r) => r.name(),
             Self::AArch64(r) => r.name(),
             Self::RiscV(r) => r.name(),
+            Self::Nvptx(r) => r.name(),
         }
     }
 
@@ -302,6 +314,7 @@ impl InlineAsmRegClass {
             Self::Arm(r) => r.suggest_class(arch, ty).map(InlineAsmRegClass::Arm),
             Self::AArch64(r) => r.suggest_class(arch, ty).map(InlineAsmRegClass::AArch64),
             Self::RiscV(r) => r.suggest_class(arch, ty).map(InlineAsmRegClass::RiscV),
+            Self::Nvptx(r) => r.suggest_class(arch, ty).map(InlineAsmRegClass::Nvptx),
         }
     }
 
@@ -321,6 +334,7 @@ impl InlineAsmRegClass {
             Self::Arm(r) => r.suggest_modifier(arch, ty),
             Self::AArch64(r) => r.suggest_modifier(arch, ty),
             Self::RiscV(r) => r.suggest_modifier(arch, ty),
+            Self::Nvptx(r) => r.suggest_modifier(arch, ty),
         }
     }
 
@@ -336,6 +350,7 @@ impl InlineAsmRegClass {
             Self::Arm(r) => r.default_modifier(arch),
             Self::AArch64(r) => r.default_modifier(arch),
             Self::RiscV(r) => r.default_modifier(arch),
+            Self::Nvptx(r) => r.default_modifier(arch),
         }
     }
 
@@ -350,6 +365,7 @@ impl InlineAsmRegClass {
             Self::Arm(r) => r.supported_types(arch),
             Self::AArch64(r) => r.supported_types(arch),
             Self::RiscV(r) => r.supported_types(arch),
+            Self::Nvptx(r) => r.supported_types(arch),
         }
     }
 
@@ -367,6 +383,7 @@ impl InlineAsmRegClass {
                 InlineAsmArch::RiscV32 | InlineAsmArch::RiscV64 => {
                     Self::RiscV(RiscVInlineAsmRegClass::parse(arch, name)?)
                 }
+                InlineAsmArch::Nvptx64 => Self::Nvptx(NvptxInlineAsmRegClass::parse(arch, name)?),
             })
         })
     }
@@ -379,6 +396,7 @@ impl InlineAsmRegClass {
             Self::Arm(r) => r.valid_modifiers(arch),
             Self::AArch64(r) => r.valid_modifiers(arch),
             Self::RiscV(r) => r.valid_modifiers(arch),
+            Self::Nvptx(r) => r.valid_modifiers(arch),
         }
     }
 }
@@ -518,5 +536,10 @@ pub fn allocatable_registers(
             riscv::fill_reg_map(arch, has_feature, &mut map);
             map
         }
+        InlineAsmArch::Nvptx64 => {
+            let mut map = nvptx::regclass_map();
+            nvptx::fill_reg_map(arch, has_feature, &mut map);
+            map
+        }
     }
 }
diff --git a/src/librustc_target/asm/nvptx.rs b/src/librustc_target/asm/nvptx.rs
new file mode 100644
index 0000000000000..43d16ae0f5d10
--- /dev/null
+++ b/src/librustc_target/asm/nvptx.rs
@@ -0,0 +1,49 @@
+use super::{InlineAsmArch, InlineAsmType};
+use rustc_macros::HashStable_Generic;
+
+def_reg_class! {
+    Nvptx NvptxInlineAsmRegClass {
+        reg16,
+        reg32,
+        reg64,
+    }
+}
+
+impl NvptxInlineAsmRegClass {
+    pub fn valid_modifiers(self, _arch: InlineAsmArch) -> &'static [char] {
+        &[]
+    }
+
+    pub fn suggest_class(self, _arch: InlineAsmArch, _ty: InlineAsmType) -> Option<Self> {
+        None
+    }
+
+    pub fn suggest_modifier(
+        self,
+        _arch: InlineAsmArch,
+        _ty: InlineAsmType,
+    ) -> Option<(char, &'static str)> {
+        None
+    }
+
+    pub fn default_modifier(self, _arch: InlineAsmArch) -> Option<(char, &'static str)> {
+        None
+    }
+
+    pub fn supported_types(
+        self,
+        _arch: InlineAsmArch,
+    ) -> &'static [(InlineAsmType, Option<&'static str>)] {
+        match self {
+            Self::reg16 => types! { _: I8, I16; },
+            Self::reg32 => types! { _: I8, I16, I32, F32; },
+            Self::reg64 => types! { _: I8, I16, I32, F32, I64, F64; },
+        }
+    }
+}
+
+def_regs! {
+    // Registers in PTX are declared in the assembly.
+    // There are no predefined registers that one can use.
+    Nvptx NvptxInlineAsmReg NvptxInlineAsmRegClass {}
+}
diff --git a/src/test/assembly/asm/nvptx-types.rs b/src/test/assembly/asm/nvptx-types.rs
new file mode 100644
index 0000000000000..4ee79d1bcc839
--- /dev/null
+++ b/src/test/assembly/asm/nvptx-types.rs
@@ -0,0 +1,133 @@
+// no-system-llvm
+// assembly-output: emit-asm
+// compile-flags: --target nvptx64-nvidia-cuda
+// compile-flags: --crate-type cdylib
+
+#![feature(no_core, lang_items, rustc_attrs)]
+#![no_core]
+
+#[rustc_builtin_macro]
+macro_rules! asm {
+    () => {};
+}
+#[rustc_builtin_macro]
+macro_rules! concat {
+    () => {};
+}
+
+#[lang = "sized"]
+trait Sized {}
+#[lang = "copy"]
+trait Copy {}
+
+type ptr = *mut u8;
+
+impl Copy for i8 {}
+impl Copy for i16 {}
+impl Copy for i32 {}
+impl Copy for f32 {}
+impl Copy for i64 {}
+impl Copy for f64 {}
+impl Copy for ptr {}
+
+// NVPTX does not support static variables
+#[no_mangle]
+fn extern_func() {}
+
+// CHECK-LABEL: .visible .func sym_fn()
+// CHECK: // begin inline asm
+// CHECK: call extern_func;
+// CHECK: // end inline asm
+#[no_mangle]
+pub unsafe fn sym_fn() {
+    asm!("call {};", sym extern_func);
+}
+
+macro_rules! check {
+    ($func:ident $ty:ident $class:ident $mov:literal) => {
+        #[no_mangle]
+        pub unsafe fn $func(x: $ty) -> $ty {
+            let y;
+            asm!(concat!($mov, " {}, {};"), out($class) y, in($class) x);
+            y
+        }
+    };
+}
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg16_i8
+// CHECK: // begin inline asm
+// CHECK: mov.i16 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg16_i8 i8 reg16 "mov.i16");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg16_i16
+// CHECK: // begin inline asm
+// CHECK: mov.i16 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg16_i16 i16 reg16 "mov.i16");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg32_i8
+// CHECK: // begin inline asm
+// CHECK: mov.i32 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg32_i8 i8 reg32 "mov.i32");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg32_i16
+// CHECK: // begin inline asm
+// CHECK: mov.i32 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg32_i16 i16 reg32 "mov.i32");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg32_i32
+// CHECK: // begin inline asm
+// CHECK: mov.i32 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg32_i32 i32 reg32 "mov.i32");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg32_f32
+// CHECK: // begin inline asm
+// CHECK: mov.i32 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg32_f32 f32 reg32 "mov.i32");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg64_i8
+// CHECK: // begin inline asm
+// CHECK: mov.i64 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg64_i8 i8 reg64 "mov.i64");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg64_i16
+// CHECK: // begin inline asm
+// CHECK: mov.i64 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg64_i16 i16 reg64 "mov.i64");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg64_i32
+// CHECK: // begin inline asm
+// CHECK: mov.i64 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg64_i32 i32 reg64 "mov.i64");
+
+// CHECK-LABEL: .visible .func (.param .b32 func_retval0) reg64_f32
+// CHECK: // begin inline asm
+// CHECK: mov.i64 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg64_f32 f32 reg64 "mov.i64");
+
+// CHECK-LABEL: .visible .func (.param .b64 func_retval0) reg64_i64
+// CHECK: // begin inline asm
+// CHECK: mov.i64 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg64_i64 i64 reg64 "mov.i64");
+
+// CHECK-LABEL: .visible .func (.param .b64 func_retval0) reg64_f64
+// CHECK: // begin inline asm
+// CHECK: mov.i64 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg64_f64 f64 reg64 "mov.i64");
+
+// CHECK-LABEL: .visible .func (.param .b64 func_retval0) reg64_ptr
+// CHECK: // begin inline asm
+// CHECK: mov.i64 %{{[a-z0-9]+}}, %{{[a-z0-9]+}};
+// CHECK: // end inline asm
+check!(reg64_ptr ptr reg64 "mov.i64");