diff --git a/src/document/patchFocus.ts b/src/document/patchFocus.ts
index f6e5d83b..fc32a6e2 100644
--- a/src/document/patchFocus.ts
+++ b/src/document/patchFocus.ts
@@ -5,7 +5,7 @@ const patched = Symbol('patched focus/blur methods')
 
 declare global {
   interface HTMLElement {
-    readonly [patched]?: Pick<HTMLElement, 'focus' | 'blur'>
+    [patched]?: Pick<HTMLElement, 'focus' | 'blur'>
   }
 }
 
@@ -93,11 +93,17 @@ export function restoreFocus(HTMLElement: typeof globalThis['HTMLElement']) {
     Object.defineProperties(HTMLElement.prototype, {
       focus: {
         configurable: true,
-        get: () => focus,
+        value: focus,
+        writable: true,
       },
       blur: {
         configurable: true,
-        get: () => blur,
+        value: blur,
+        writable: true,
+      },
+      [patched]: {
+        configurable: true,
+        get: () => undefined,
       },
     })
   }
diff --git a/src/index.ts b/src/index.ts
index c5e3cdd1..e04ad50f 100644
--- a/src/index.ts
+++ b/src/index.ts
@@ -1,8 +1,32 @@
 // the default export is kept for backward compatibility only...
 export {userEvent as default} from './setup'
 
-export {userEvent} from './setup'
+export {userEvent, prepare, reset, detach} from './setup'
 export type {UserEvent} from './setup/setup'
 export type {keyboardKey} from './system/keyboard'
 export type {pointerKey} from './system/pointer'
 export {PointerEventsCheckLevel, type Options} from './options'
+
+import {reset, detach} from './setup'
+
+const g = globalThis as {
+  afterEach?: (cb?: () => void) => void
+  afterAll?: (cb?: () => void) => void
+  window?: Window & typeof globalThis
+}
+
+if (typeof g.afterEach === 'function') {
+  g.afterEach(() => {
+    if (g.window) {
+      reset(g.window)
+    }
+  })
+}
+
+if (typeof g.afterAll === 'function') {
+  g.afterAll(() => {
+    if (g.window) {
+      detach(g.window)
+    }
+  })
+}
diff --git a/src/setup/index.ts b/src/setup/index.ts
index b0308f38..f2328c72 100644
--- a/src/setup/index.ts
+++ b/src/setup/index.ts
@@ -7,3 +7,9 @@ export const userEvent = {
   ...directApi,
   setup: setupMain,
 } as const
+
+export {
+  prepare,
+  reset,
+  detach,
+} from './setup'
diff --git a/src/setup/setup.ts b/src/setup/setup.ts
index 9475a4c2..c9747efa 100644
--- a/src/setup/setup.ts
+++ b/src/setup/setup.ts
@@ -1,4 +1,4 @@
-import {patchFocus} from '../document/patchFocus'
+import {patchFocus, restoreFocus} from '../document/patchFocus'
 import {prepareDocument} from '../document/prepareDocument'
 import {dispatchEvent, dispatchUIEvent} from '../event'
 import {defaultKeyMap as defaultKeyboardMap} from '../keyboard/keyMap'
@@ -7,8 +7,10 @@ import {Options, PointerEventsCheckLevel} from '../options'
 import {
   ApiLevel,
   attachClipboardStubToView,
+  detachClipboardStubFromView,
   getDocumentFromNode,
   getWindow,
+  resetClipboardStubOnView,
   setLevelRef,
   wait,
 } from '../utils'
@@ -83,12 +85,9 @@ export function createConfig(
  */
 export function setupMain(options: Options = {}) {
   const config = createConfig(options)
-  prepareDocument(config.document)
-  patchFocus(getWindow(config.document).HTMLElement)
 
-  const view =
-    config.document.defaultView ?? /* istanbul ignore next */ globalThis.window
-  attachClipboardStubToView(view)
+  const view = getWindow(config.document)
+  _prepare(view)
 
   return createInstance(config).api
 }
@@ -105,8 +104,9 @@ export function setupDirect(
   node?: Node,
 ) {
   const config = createConfig(options, defaultOptionsDirect, node)
-  prepareDocument(config.document)
-  patchFocus(getWindow(config.document).HTMLElement)
+
+  const view = getWindow(config.document)
+  _prepare(view, false)
 
   const system = pointerState ?? keyboardState ?? new System()
 
@@ -182,3 +182,44 @@ function getDocument(
     options.document ?? (node && getDocumentFromNode(node)) ?? defaults.document
   )
 }
+
+function _prepare(
+  view: Window & typeof globalThis,
+  attachClipboardStub = true,
+) {
+  prepareDocument(view.document)
+  patchFocus(view.HTMLElement)
+
+  if (attachClipboardStub) {
+    attachClipboardStubToView(view)
+  }
+}
+
+/**
+ * @experimental
+ */
+export function prepare(
+  view: Window & typeof globalThis,
+) {
+  _prepare(view)
+}
+
+/**
+ * @experimental
+ */
+export function reset(
+  view: Window & typeof globalThis,
+) {
+  restoreFocus(view.HTMLElement)
+  resetClipboardStubOnView(view)
+}
+
+/**
+ * @experimental
+ */
+export function detach(
+  view: Window & typeof globalThis,
+) {
+  restoreFocus(view.HTMLElement)
+  detachClipboardStubFromView(view)
+}
diff --git a/src/utils/dataTransfer/Clipboard.ts b/src/utils/dataTransfer/Clipboard.ts
index 7b933695..e8e77580 100644
--- a/src/utils/dataTransfer/Clipboard.ts
+++ b/src/utils/dataTransfer/Clipboard.ts
@@ -209,17 +209,3 @@ export async function writeDataTransferToClipboard(
     throw new Error('The Clipboard API is unavailable.')
   }
 }
-
-const g = globalThis as {
-  afterEach?: (cb?: () => void) => void
-  afterAll?: (cb?: () => void) => void
-}
-/* istanbul ignore else */
-if (typeof g.afterEach === 'function') {
-  g.afterEach(() => resetClipboardStubOnView(globalThis.window))
-}
-
-/* istanbul ignore else */
-if (typeof g.afterAll === 'function') {
-  g.afterAll(() => detachClipboardStubFromView(globalThis.window))
-}