diff --git a/packages/runtime-core/__tests__/components/Suspense.spec.ts b/packages/runtime-core/__tests__/components/Suspense.spec.ts
index 8de5b3182d0..fe807c6dfaa 100644
--- a/packages/runtime-core/__tests__/components/Suspense.spec.ts
+++ b/packages/runtime-core/__tests__/components/Suspense.spec.ts
@@ -472,6 +472,124 @@ describe('Suspense', () => {
     expect(calls).toEqual([])
   })
 
+  // #10042
+  test('unmount suspensible child before parent suspense resolve', async () => {
+    const calls: string[] = []
+
+    const OuterB = defineAsyncComponent(
+      {
+        setup: () => {
+          onMounted(() => {
+            calls.push('OuterB mounted')
+          })
+          onUnmounted(() => {
+            calls.push('OuterB unmounted')
+          })
+          return () => h('div', 'OuterB')
+        },
+      },
+      10,
+    )
+
+    const OuterA = defineAsyncComponent(
+      {
+        setup: () => {
+          onMounted(() => {
+            calls.push('OuterA mounted')
+          })
+          onUnmounted(() => {
+            calls.push('OuterA unmounted')
+          })
+          return () =>
+            h('div', null, [
+              h('div', 'OuterA'),
+              h(RouterView, null, {
+                default: ({ Component }: any) => [
+                  Component
+                    ? h(
+                        Suspense,
+                        { suspensible: true },
+                        {
+                          default: () => h(Component),
+                        },
+                      )
+                    : null,
+                ],
+              }),
+            ])
+        },
+      },
+      10,
+    )
+
+    const InnerA = defineAsyncComponent(
+      {
+        setup: () => {
+          onMounted(() => {
+            calls.push('InnerA mounted')
+          })
+          onUnmounted(() => {
+            calls.push('InnerA unmounted')
+          })
+          return () => h('div', 'InnerA')
+        },
+      },
+      5,
+    )
+
+    const toggle = ref(true)
+    const route = computed(() => {
+      return toggle.value ? [OuterA, InnerA] : [OuterB]
+    })
+
+    const Comp = {
+      setup() {
+        provide('route', route)
+        return () =>
+          h(RouterView, null, {
+            default: ({ Component }: any) => [
+              h(Suspense, null, {
+                default: () => h(Component),
+              }),
+            ],
+          })
+      },
+    }
+
+    const root = nodeOps.createElement('div')
+    render(h(Comp), root)
+    await Promise.all(deps)
+    await nextTick()
+    expect(serializeInner(root)).toBe(`<!---->`)
+
+    await Promise.all(deps)
+    await nextTick()
+    expect(serializeInner(root)).toBe(
+      `<div><div>OuterA</div><div>InnerA</div></div>`,
+    )
+    expect(calls).toEqual([`OuterA mounted`, 'InnerA mounted'])
+
+    deps.length = 0
+    calls.length = 0
+    toggle.value = false
+    await nextTick()
+
+    // expect not change
+    expect(serializeInner(root)).toBe(
+      `<div><div>OuterA</div><div>InnerA</div></div>`,
+    )
+    expect(calls).toEqual([])
+
+    await Promise.all(deps)
+    await nextTick()
+    expect(serializeInner(root)).toBe(`<div>OuterB</div>`)
+    expect(calls).toEqual([
+      'OuterB mounted',
+      'InnerA unmounted',
+      'OuterA unmounted',
+    ])
+  })
+
   test('unmount suspense after resolve', async () => {
     const toggle = ref(true)
     const unmounted = vi.fn()
diff --git a/packages/runtime-core/src/components/Suspense.ts b/packages/runtime-core/src/components/Suspense.ts
index e9723f23652..4a43452334a 100644
--- a/packages/runtime-core/src/components/Suspense.ts
+++ b/packages/runtime-core/src/components/Suspense.ts
@@ -425,6 +425,7 @@ export interface SuspenseBoundary {
   isInFallback: boolean
   isHydrating: boolean
   isUnmounted: boolean
+  preEffects: Function[]
   effects: Function[]
   resolve(force?: boolean, sync?: boolean): void
   fallback(fallbackVNode: VNode): void
@@ -506,6 +507,7 @@ function createSuspenseBoundary(
     isInFallback: !isHydrating,
     isHydrating,
     isUnmounted: false,
+    preEffects: [],
     effects: [],
 
     resolve(resume = false, sync = false) {
@@ -526,6 +528,7 @@ function createSuspenseBoundary(
         activeBranch,
         pendingBranch,
         pendingId,
+        preEffects,
         effects,
         parentComponent,
         container,
@@ -536,6 +539,10 @@ function createSuspenseBoundary(
       if (suspense.isHydrating) {
         suspense.isHydrating = false
       } else if (!resume) {
+        if (preEffects.length > 0) {
+          preEffects.forEach(e => e())
+          suspense.preEffects = []
+        }
         delayEnter =
           activeBranch &&
           pendingBranch!.transition &&
@@ -901,3 +908,15 @@ function isVNodeSuspensible(vnode: VNode) {
   const suspensible = vnode.props && vnode.props.suspensible
   return suspensible != null && suspensible !== false
 }
+
+export function hasSuspensibleChild(vnode: VNode): boolean {
+  if (vnode.shapeFlag & ShapeFlags.SUSPENSE && isVNodeSuspensible(vnode)) {
+    return true
+  }
+
+  if (isArray(vnode.children)) {
+    return vnode.children.some(child => hasSuspensibleChild(child as VNode))
+  }
+
+  return false
+}
diff --git a/packages/runtime-core/src/renderer.ts b/packages/runtime-core/src/renderer.ts
index d5c5b6d8dfb..cbf65b41706 100644
--- a/packages/runtime-core/src/renderer.ts
+++ b/packages/runtime-core/src/renderer.ts
@@ -56,6 +56,7 @@ import { setRef } from './rendererTemplateRef'
 import {
   type SuspenseBoundary,
   type SuspenseImpl,
+  hasSuspensibleChild,
   queueEffectWithSuspense,
 } from './components/Suspense'
 import type { TeleportImpl, TeleportVNode } from './components/Teleport'
@@ -1583,8 +1584,22 @@ function baseCreateRenderer(
     ))
 
     const update: SchedulerJob = (instance.update = () => {
-      if (effect.dirty) {
-        effect.run()
+      const job = () => {
+        if (effect.dirty) {
+          effect.run()
+        }
+      }
+
+      if (
+        __FEATURE_SUSPENSE__ &&
+        parentSuspense &&
+        parentSuspense.deps > 0 &&
+        instance.subTree &&
+        hasSuspensibleChild(instance.subTree)
+      ) {
+        parentSuspense.preEffects.push(job)
+      } else {
+        job()
       }
     })
     update.id = instance.uid