DDRi collab AZ-IGI (UCSF)

Notebooks

Final analysis notebooks:

• evaluate-DDRi-v2-screens
• drug-gene-knowledge-graph
• evaluate-DDRi-PRDX1-v3-screens
• build-interactive-plots
• PRDX1-6-CanDI-analysis

Interactive Plots

Locally displayed interactive plots using streamlit:

streamlit run app/DDRi_Screens_app.py

Data Overview

List of FASTQ files for all the screens: checksums list

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Sample name format:

<study_model>__<platform>__<perturbation>__<replicate>

e.g.

A549__CRISPRa_v2__DMSO__rep1.fastq.gz
A549_PRDX1KO__CRISPRi_v3__DNAPKi__rep1_R1.fastq.gz