On the Qt Py, board.NEOPIXEL_POWER cannot be controlled, by, say, doing digitalio.DigitalInOut(board.NEOPIXEL_POWER). The pin is always in use, because it is set to high in board.c and also set to never reset. But if the never_reset is removed, then the pin does get reset, and the status NeoPixel goes out. So it needs to be special-cased in some way.